Literature DB >> 30923969

Lineage-specific roles of hedgehog-GLI signaling during mammalian kidney development.

Robert D'Cruz1,2, Katryna Stronks1,2, Christopher J Rowan2, Norman D Rosenblum3,4,5,6,7.   

Abstract

Aberrant hedgehog (Hh) signaling during embryogenesis results in various severe congenital abnormalities, including renal malformations. The molecular mechanisms that underlie congenital renal malformations remain poorly understood. Here, we review the current understanding of the lineage-specific roles of Hh signaling during renal morphogenesis and how aberrant Hh signaling during embryonic kidney development contributes to renal malformation.

Entities:  

Keywords:  GLI; Hedgehog; Nephron; Pallister-Hall syndrome; Stroma; Ureteric

Mesh：

Substances：

Year:  2019        PMID： 30923969     DOI： 10.1007/s00467-019-04240-8

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN： 0931-041X            Impact factor:   3.714


  51 in total

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Authors:  James Briscoe; Pascal P Thérond
Journal:  Nat Rev Mol Cell Biol       Date:  2013-05-30       Impact factor: 94.444

2.  Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog.

Authors:  J Motoyama; T Takabatake; K Takeshima; C Hui
Journal:  Nat Genet       Date:  1998-02       Impact factor: 38.330

3.  Developmental origins and functions of stromal cells in the normal and diseased mammalian kidney.

Authors:  Winny Li; Sunny Hartwig; Norman D Rosenblum
Journal:  Dev Dyn       Date:  2014-04-17       Impact factor: 3.780

Review 4.  Hedgehog Signaling: From Basic Biology to Cancer Therapy.

Authors:  Fujia Wu; Yu Zhang; Bo Sun; Andrew P McMahon; Yu Wang
Journal:  Cell Chem Biol       Date:  2017-03-09       Impact factor: 8.116

5.  Severe Pallister-Hall syndrome with persistent urogenital sinus, renal agenesis, imperforate anus, bilateral hypothalamic hamartomas, and severe skeletal anomalies.

Authors:  Elizabeth McPherson; Christopher Cold
Journal:  Am J Med Genet A       Date:  2013-08-15       Impact factor: 2.802

6.  Molecular and clinical analyses of Greig cephalopolysyndactyly and Pallister-Hall syndromes: robust phenotype prediction from the type and position of GLI3 mutations.

Authors:  Jennifer J Johnston; Isabelle Olivos-Glander; Christina Killoran; Emma Elson; Joyce T Turner; Kathryn F Peters; Margaret H Abbott; David J Aughton; Arthur S Aylsworth; Michael J Bamshad; Carol Booth; Cynthia J Curry; Albert David; Mary Beth Dinulos; David B Flannery; Michelle A Fox; John M Graham; Dorothy K Grange; Alan E Guttmacher; Mark C Hannibal; Wolfram Henn; Raoul C M Hennekam; Lewis B Holmes; H Eugene Hoyme; Kathleen A Leppig; Angela E Lin; Patrick Macleod; David K Manchester; Carlo Marcelis; Laura Mazzanti; Emma McCann; Marie T McDonald; Nancy J Mendelsohn; John B Moeschler; Billur Moghaddam; Giovanni Neri; Ruth Newbury-Ecob; Roberta A Pagon; John A Phillips; Laurie S Sadler; Joan M Stoler; David Tilstra; Catherine M Walsh Vockley; Elaine H Zackai; Touran M Zadeh; Louise Brueton; Graeme Charles M Black; Leslie G Biesecker
Journal:  Am J Hum Genet       Date:  2005-02-28       Impact factor: 11.025

Review 7.  Genital abnormalities in Pallister-Hall syndrome: Report of two patients and review of the literature.

Authors:  Yoko Narumi; Tomoki Kosho; Goro Tsuruta; Masaaki Shiohara; Ei Shimazaki; Tetsuo Mori; Ayako Shimizu; Yasuhiko Igawa; Shuji Nishizawa; Kimiyo Takagi; Rie Kawamura; Keiko Wakui; Yoshimitsu Fukushima
Journal:  Am J Med Genet A       Date:  2010-12       Impact factor: 2.802

8.  Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development.

Authors:  Yong Pan; Chengbing Wang; Baolin Wang
Journal:  Dev Biol       Date:  2008-11-20       Impact factor: 3.582

9.  Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor.

Authors:  Joshua Blake; Di Hu; Jason E Cain; Norman D Rosenblum
Journal:  Hum Mol Genet       Date:  2015-11-24       Impact factor: 6.150

10.  Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney.

Authors:  Jing Yu; Thomas J Carroll; Andrew P McMahon
Journal:  Development       Date:  2002-11       Impact factor: 6.868
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  7 in total

Review 1.  The origin and role of the renal stroma.

Authors:  Sean B Wilson; Melissa H Little
Journal:  Development       Date:  2021-09-23       Impact factor: 6.862

2.  Protein Kinase A Downregulation Delays the Development and Progression of Polycystic Kidney Disease.

Authors:  Xiaofang Wang; Li Jiang; Ka Thao; Caroline R Sussman; Timothy LaBranche; Michael Palmer; Peter C Harris; G Stanley McKnight; Klaus P Hoeflich; Stefanie Schalm; Vicente E Torres
Journal:  J Am Soc Nephrol       Date:  2022-03-02       Impact factor: 14.978

3.  Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.

Authors:  Nelly M Cruz; Raghava Reddy; José L McFaline-Figueroa; Christine Tran; Hongxia Fu; Benjamin S Freedman
Journal:  Nat Biomed Eng       Date:  2022-04-27       Impact factor: 29.234

Review 4.  Cilia in cystic kidney and other diseases.

Authors:  Gregory J Pazour; Lynne Quarmby; Abigail O Smith; Paurav B Desai; Miriam Schmidts
Journal:  Cell Signal       Date:  2019-12-24       Impact factor: 4.315

5.  Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.

Authors:  Shichao Duan; Hao Li; Yirong Zhang; Suming Yang; Yawen Chen; Benhua Qiu; Cheng Huang; Juan Wang; Jinsong Li; Xueliang Zhu; Xiumin Yan
Journal:  EMBO J       Date:  2020-11-26       Impact factor: 11.598

6.  The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease.

Authors:  Jennifer Arroyo; Diana Escobar-Zarate; Harrison H Wells; Megan M Constans; Ka Thao; Jessica M Smith; Cynthia J Sieben; Madeline R Martell; Timothy L Kline; Maria V Irazabal; Vicente E Torres; Katharina Hopp; Peter C Harris
Journal:  Kidney Int       Date:  2021-03-09       Impact factor: 18.998

Review 7.  Transforming growth factor beta signaling functions during mammalian kidney development.

Authors:  Mihai G Dumbrava; Jon L Lacanlale; Christopher J Rowan; Norman D Rosenblum
Journal:  Pediatr Nephrol       Date:  2020-09-03       Impact factor: 3.714
  7 in total

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