Literature DB >> 30923423

Has the Scottish Managed Clinical Network for Sarcoma influenced the survival outcomes for primary malignant bone tumours?

F MacDonald1, S Gupta1.   

Abstract

Primary malignant bone tumours (PMBT) are rare. We have reviewed patient outcomes in Scotland over a 20 year period and provided an update on the principles of current management strategies for the non-specialist practitioner. The Scottish Managed Clinical Network for Sarcoma (MCN) connects the three main management centres for sarcoma in Scotland: Glasgow, Aberdeen and Edinburgh. Prior to the formation of the MCN, all centres were connected via the Scottish Bone Tumour Registry (SBTR), where they would meet on a quarterly basis and all the bone/soft tissue tumour cases were discussed retrospectively. The MCN was introduced in 2006. Our primary aims were to assess the impact of the MCN on patient outcomes and to update clinicians on the recognition, assessment and staging of PMBT. A secondary aim was to compare results from the Scottish centres with other UK sites. The patient information was gathered from the Scottish Bone Tumour Registry, held at the Queen Elizabeth University Hospital in Glasgow. All patients with diagnoses of Osteosarcoma, Chondrosarcoma and Ewing Sarcoma between 1994 and 2014 were included. Results showed that there was no significant change in outcome following the formation of the Scottish Managed Clinical Network for Sarcoma, and that there were little differences in outcome amongst the three major management centres in Scotland. Findings also show Scotland to have similar outcomes to that of the rest of the UK following diagnosis of a primary malignant bone tumour.

Entities:  

Year:  2019        PMID: 30923423      PMCID: PMC6423303          DOI: 10.1016/j.jor.2019.02.027

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  19 in total

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2.  Size matters for sarcomas!

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Authors:  Bruno Fuchs; Douglas J Pritchard
Journal:  Clin Orthop Relat Res       Date:  2002-04       Impact factor: 4.176

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Authors:  M F Hansen; M J Nellissery; P Bhatia
Journal:  J Bone Miner Res       Date:  1999-10       Impact factor: 6.741

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Authors:  S Goyal; J Roscoe; W D J Ryder; H R Gattamaneni; T O B Eden
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7.  Mesenchymal chondrosarcoma of soft tissues and bone in children, adolescents, and young adults: experiences of the CWS and COSS study groups.

Authors:  Tobias M Dantonello; Christoph Int-Veen; Ivo Leuschner; Andreas Schuck; Rhoikos Furtwaengler; Alexander Claviez; Dominik T Schneider; Thomas Klingebiel; Stefan S Bielack; Ewa Koscielniak
Journal:  Cancer       Date:  2008-06       Impact factor: 6.860

Review 8.  Ollier disease.

Authors:  Caroline Silve; Harald Jüppner
Journal:  Orphanet J Rare Dis       Date:  2006-09-22       Impact factor: 4.123

9.  Ewing's Sarcoma of the Upper Extremity: Presenting Symptoms, Diagnostic Delay and Outcome.

Authors:  Philip M S Simpson; Robin Reid; Daniel Porter
Journal:  Sarcoma       Date:  2005

10.  Mesenchymal chondrosarcoma. An analysis of patients treated at a single institution.

Authors:  Marilena Cesari; Franco Bertoni; Patrizia Bacchini; Mario Mercuri; Emanuela Palmerini; Stefano Ferrari
Journal:  Tumori       Date:  2007 Sep-Oct
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  1 in total

1.  Expression of HER-2 in surgical specimen and biopsy as a biomarker of metastasis in patients with osteosarcoma: a meta-analysis.

Authors:  Jian Zhou; Wanchun Wang; Qian Yan; Yingquan Luo
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  1 in total

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