Literature DB >> 309010

Homozygous alpha1 antitrypsin deficiency with unusual associations: a case report.

R C Young, V E Headings, S Bose, R L Hackney.   

Abstract

The rare association of protease inhibitor deficiency (Pi(zz) genotype) in a black American with chronic, obstructive pulmonary disease due to asthmatic bronchitis, rather than basal pan lobular emphysema, is presented. The late onset of symptoms, despite environmental exposures, is also unusual in this homozygote, as is his ethnic background.

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Year:  1978        PMID: 309010      PMCID: PMC2537061     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  11 in total

1.  EXPERIMENTAL EMPHYSEMA: ITS PRODUCTION WITH PAPAIN IN NORMAL AND SILICOTIC RATS.

Authors:  P GROSS; E A PFITZER; E TOLKER; M A BABYAK; M KASCHAK
Journal:  Arch Environ Health       Date:  1965-07

2.  The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men.

Authors:  R C KORY; R CALLAHAN; H G BOREN; J C SYNER
Journal:  Am J Med       Date:  1961-02       Impact factor: 4.965

3.  Antitrypsin phenotypes in St. Louis.

Authors:  J A Pierce; B Eradio; T A Dew
Journal:  JAMA       Date:  1975-02-10       Impact factor: 56.272

4.  Pathophysiology of hereditary emphysema.

Authors:  P M Stevens; V S Hnilica; P C Johnson; R L Bell
Journal:  Ann Intern Med       Date:  1971-05       Impact factor: 25.391

5.  Heterozygous and homozygous alpha1-antitrypsin deficiency in patients with pulmonary emphysema.

Authors:  J Lieberman
Journal:  N Engl J Med       Date:  1969-08-07       Impact factor: 91.245

6.  Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

Authors:  H L Sharp; R A Bridges; W Krivit; E F Freier
Journal:  J Lab Clin Med       Date:  1969-06

7.  Antitrypsin deficiency in pulmonary disease: the significance of intermediate levels.

Authors:  M H Welch; M E Reinecke; J F Hammarsten; C A Guenter
Journal:  Ann Intern Med       Date:  1969-09       Impact factor: 25.391

8.  Prevalence of of alpha 1-antitrypsin Pi types among newborn infants of different ethnic backgrounds.

Authors:  H E Evans; N S Bognacki; L M Perrott; L Glass
Journal:  J Pediatr       Date:  1977-04       Impact factor: 4.406

9.  Clinical, epidemiologic, and pulmonary function studies in alpha,-antitrypsin-deficient subjects of Pi Z type.

Authors:  W Rawlings; P Kreiss; D Levy; B Cohen; H Menkes; S Brashears; S Permutt
Journal:  Am Rev Respir Dis       Date:  1976-11

10.  A possible experimental approach to the association of hereditary alpha-1-antitrypsin deficiency and pulmonary emphysema.

Authors:  F Kueppers; A G Bearn
Journal:  Proc Soc Exp Biol Med       Date:  1966-04
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