Literature DB >> 30890539

Beyond sensing DNA: a role for cGAS in the detection of extracellular cyclic di-nucleotides.

Leonie Unterholzner1.   

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Year:  2019        PMID： 30890539      PMCID： PMC6446196          DOI： 10.15252/embr.201947970

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


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  9 in total

Review 1.  Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.

Authors:  Qi Chen; Lijun Sun; Zhijian J Chen
Journal:  Nat Immunol       Date:  2016-09-20       Impact factor: 25.606

2.  The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity.

Authors:  Pengyan Xia; Shuo Wang; Zhen Xiong; Xiaoxiao Zhu; Buqing Ye; Ying Du; Shu Meng; Yuan Qu; Jing Liu; Guangxia Gao; Yong Tian; Zusen Fan
Journal:  Nat Immunol       Date:  2018-01-01       Impact factor: 25.606

3.  Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

Authors:  Adelle P McFarland; Shukun Luo; Fariha Ahmed-Qadri; Meghan Zuck; Elizabeth F Thayer; Young Ah Goo; Kevin Hybiske; Liang Tong; Joshua J Woodward
Journal:  Immunity       Date:  2017-03-21       Impact factor: 31.745

4.  STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors.

Authors:  Seng-Ryong Woo; Mercedes B Fuertes; Leticia Corrales; Stefani Spranger; Michael J Furdyna; Michael Y K Leung; Ryan Duggan; Ying Wang; Glen N Barber; Katherine A Fitzgerald; Maria-Luisa Alegre; Thomas F Gajewski
Journal:  Immunity       Date:  2014-11-05       Impact factor: 31.745

5.  NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation.

Authors:  Xavier Lahaye; Matteo Gentili; Aymeric Silvin; Cécile Conrad; Léa Picard; Mabel Jouve; Elina Zueva; Mathieu Maurin; Francesca Nadalin; Gavin J Knott; Baoyu Zhao; Fenglei Du; Marlène Rio; Jeanne Amiel; Archa H Fox; Pingwei Li; Lucie Etienne; Charles S Bond; Laurence Colleaux; Nicolas Manel
Journal:  Cell       Date:  2018-09-27       Impact factor: 41.582

6.  Nuclear cGAS suppresses DNA repair and promotes tumorigenesis.

Authors:  Haipeng Liu; Haiping Zhang; Xiangyang Wu; Dapeng Ma; Juehui Wu; Lin Wang; Yan Jiang; Yiyan Fei; Chenggang Zhu; Rong Tan; Peter Jungblut; Gang Pei; Anca Dorhoi; Qiaoling Yan; Fan Zhang; Ruijuan Zheng; Siyu Liu; Haijiao Liang; Zhonghua Liu; Hua Yang; Jianxia Chen; Peng Wang; Tianqi Tang; Wenxia Peng; Zhangsen Hu; Zhu Xu; Xiaochen Huang; Jie Wang; Haohao Li; Yilong Zhou; Feng Liu; Dapeng Yan; Stefan H E Kaufmann; Chang Chen; Zhiyong Mao; Baoxue Ge
Journal:  Nature       Date:  2018-10-24       Impact factor: 49.962

7.  The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response.

Authors:  Kislay Parvatiyar; Zhiqiang Zhang; Rosane M Teles; Songying Ouyang; Yan Jiang; Shankar S Iyer; Shivam A Zaver; Mirjam Schenk; Shang Zeng; Wenwan Zhong; Zhi-Jie Liu; Robert L Modlin; Yong-jun Liu; Genhong Cheng
Journal:  Nat Immunol       Date:  2012-11-11       Impact factor: 25.606

8.  STING is a direct innate immune sensor of cyclic di-GMP.

Authors:  Dara L Burdette; Kathryn M Monroe; Katia Sotelo-Troha; Jeff S Iwig; Barbara Eckert; Mamoru Hyodo; Yoshihiro Hayakawa; Russell E Vance
Journal:  Nature       Date:  2011-09-25       Impact factor: 49.962

9.  Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.

Authors:  Gillian Dunphy; Sinéad M Flannery; Jessica F Almine; Dympna J Connolly; Christina Paulus; Kasper L Jønsson; Martin R Jakobsen; Michael M Nevels; Andrew G Bowie; Leonie Unterholzner
Journal:  Mol Cell       Date:  2018-09-06       Impact factor: 17.970
  9 in total

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