Literature DB >> 30888674

Uterine Fibroids - Current Trends and Strategies.

Marcel Grube1, Felix Neis1, Sara Y Brucker1, Stefan Kommoss1, Jürgen Andress1, Martin Weiss1, Sascha Hoffmann1, Florin-Andrei Taran1, Bernhard Krämer1.   

Abstract

Fibroids are the most common benign tumors in women of childbearing age and can be found in almost 80-90% of all women by age 50 years. They can cause pain, excessive menstrual bleeding or infertility. The development of fibroids increases with age. Since the age of women in industrial countries who are trying to conceive is generally increasing, there has been a growing demand for minimally invasive and uterine-sparing surgical treatment of fibroids. Whereas the main focus of previous surgical techniques for the treatment of fibroids was enucleation of the tumour with subsequent closure of the uterine incision, modern devices developed over the past decade can destroy fibroids by using ultrasound or radio-frequency without incising the uterine wall. Thus, there is no uterine scar, which would impart a risk of rupture during labour or pregnancy. This article provides an overview of the latest techniques and devices used for uterine-sparing surgical treatment of fibroids. While laparoscopic myomectomy is still the gold standard, novel laparoscopic and transcervical radiofrequency ablation techniques use low-voltage and alternating current to induce heat in the uterine tissue, which triggers necrosis in fibroids. This enables the removal of multiple fibroids without the need for large incisions in the uterine wall. In addition, we address the benefits and potential risks, as well as the impact on fertility and pregnancy, of the different surgical approaches used for the treatment of uterine fibroids.

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Mesh:

Year:  2019        PMID: 30888674

Source DB:  PubMed          Journal:  Surg Technol Int        ISSN: 1090-3941


  7 in total

1.  Comparison of safety and efficacy between laparoscopic myomectomy and traditional laparotomy for patients with uterine fibroids and their effect on pregnancy rate after surgery.

Authors:  Xueqiao Kan; Xiaoxia Shen; Li Feng; Yuqing Hu; Jiadong Yu; Xiaoju Yang
Journal:  Exp Ther Med       Date:  2021-06-29       Impact factor: 2.447

2.  Magnetic Resonance-Guided High-Intensity Focused Ultrasound Ablation of Uterine Fibroids-Efficiency Assessment with the Use of Dynamic Contrast-Enhanced Magnetic Resonance Imaging and the Potential Role of the Administration of Uterotonic Drugs.

Authors:  Tomasz Łoziński; Michał Ciebiera; Elżbieta Łuczyńska; Justyna Filipowska; Artur Czekierdowski
Journal:  Diagnostics (Basel)       Date:  2021-04-16

3.  Clinical Value of Body Mass Index and Waist-Hip Ratio in Clinicopathological Characteristics and Prognosis of Uterine Leiomyomata.

Authors:  Hanyi Pan; Feiyong Qin; Fengyun Deng
Journal:  Evid Based Complement Alternat Med       Date:  2021-08-11       Impact factor: 2.629

4.  Uterine fibroids increase the risk of preterm birth and other adverse birth events: a systematic review and meta-analysis.

Authors:  Xiuling Wang; Gui Wang; Ru Han; Mei Gao; Fangmin Wang; Yarong Hong; Qiuxia Chen
Journal:  Transl Pediatr       Date:  2022-06

Review 5.  Uterine Fibroids and Pregnancy: How Do They Affect Each Other?

Authors:  Larissa M Coutinho; Wiviane A Assis; Ananda Spagnuolo-Souza; Fernando M Reis
Journal:  Reprod Sci       Date:  2021-06-17       Impact factor: 2.924

6.  Inhibiting effect of miR-29 on proliferation and migration of uterine leiomyoma via the STAT3 signaling pathway.

Authors:  Dai Huang; Hongyuan Xue; Weihua Shao; Xiaoxi Wang; Hongjuan Liao; Yuquan Ye
Journal:  Aging (Albany NY)       Date:  2022-02-02       Impact factor: 5.682

7.  Association between tumor necrosis factor α and uterine fibroids: A protocol of systematic review.

Authors:  Li-Nan Gao; Lian-Gang Ge; Ming-Zhe Zhu; Xin-Xin Yao
Journal:  Medicine (Baltimore)       Date:  2020-08-14       Impact factor: 1.817

  7 in total

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