Literature DB >> 30888467

The 2018 Nobel Prize in Chemistry: phage display of peptides and antibodies.

Rodrigo Barderas1, Elena Benito-Peña2.   

Abstract

One-half of the 2018 Nobel Prize in Chemistry was awarded jointly to George P. Smith and Sir Gregory P. Winter "for the phage display of peptides and antibodies". This feature article summarizes significant achievements leading to the development of phage display of peptides and antibodies, where a bacteriophage is genetically modified to display peptides and proteins, with the primary aim of producing new biopharmaceuticals. These significant achievements are proven to be useful for the development of phage-based bioassays and biosensors.

Entities:  

Keywords:  Biopharmaceuticals; Nobel Prize 2018; Phage display of peptides and proteins; Therapeutic antibodies

Mesh:

Substances:

Year:  2019        PMID: 30888467     DOI: 10.1007/s00216-019-01714-4

Source DB:  PubMed          Journal:  Anal Bioanal Chem        ISSN: 1618-2642            Impact factor:   4.142


  18 in total

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3.  Analytical applications of biomimetic recognition elements - an update.

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Journal:  Anal Bioanal Chem       Date:  2021-07-24       Impact factor: 4.142

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Review 5.  Reassessing therapeutic antibodies for neglected and tropical diseases.

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Journal:  PLoS Negl Trop Dis       Date:  2020-01-30

6.  Human Hexa-Histidine-Tagged Single-Chain Variable Fragments for Bioimaging of Bacterial Infections.

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Review 7.  Recent Advances in Monoclonal Antibody Therapy for Colorectal Cancers.

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Journal:  Biomedicines       Date:  2021-01-05

Review 8.  Phage Display Technique as a Tool for Diagnosis and Antibody Selection for Coronaviruses.

Authors:  Taruna Anand; Nitin Virmani; Bidhan C Bera; Rajesh K Vaid; Medhavi Vashisth; Priyanka Bardajatya; Ashok Kumar; Bhupendra N Tripathi
Journal:  Curr Microbiol       Date:  2021-03-09       Impact factor: 2.188

Review 9.  Current and future advances in fluorescence-based visualization of plant cell wall components and cell wall biosynthetic machineries.

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Journal:  Biotechnol Biofuels       Date:  2021-03-29       Impact factor: 6.040

Review 10.  Human immunology and immunotherapy: main achievements and challenges.

Authors:  Jezabel Varadé; Susana Magadán; África González-Fernández
Journal:  Cell Mol Immunol       Date:  2020-09-02       Impact factor: 22.096

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