Literature DB >> 3088279

Growth of Clostridium difficile and production of toxins A and B in complex and defined media.

S C Haslam, J M Ketley, T J Mitchell, J Stephen, D W Burdon, D C Candy.   

Abstract

The ability of several strains of Clostridium difficile to grow and to produce toxins A and B in complex and defined culture media has been studied with special reference to the amino-acid composition of the medium. The production of these toxins varied with the strain used and with the composition of the growth medium. Toxin A production was not inextricably linked to production of toxin B since conditions were found in which only one or other toxin was produced.

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Year:  1986        PMID: 3088279     DOI: 10.1099/00222615-21-4-293

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN: 0022-2615            Impact factor:   2.472


  32 in total

Review 1.  Pathogenesis and treatment of Clostridium difficile infection.

Authors:  I Tonna; P D Welsby
Journal:  Postgrad Med J       Date:  2005-06       Impact factor: 2.401

2.  Asymptomatic carriage of Clostridium difficile in patients with cystic fibrosis.

Authors:  S L Peach; S P Borriello; H Gaya; F E Barclay; A R Welch
Journal:  J Clin Pathol       Date:  1986-09       Impact factor: 3.411

3.  Usefulness of semi-quantitative cultures in the diagnosis of Clostridium difficile associated disease.

Authors:  L Poirier; F Lamothe; J Vincelette; A M Bourgault
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-09       Impact factor: 3.267

4.  Production of Clostridium difficile toxin in a medium totally free of both animal and dairy proteins or digests.

Authors:  Aiqi Fang; Donald F Gerson; Arnold L Demain
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-27       Impact factor: 11.205

5.  Sequence variation in tcdA and tcdB of Clostridium difficile: ST37 with truncated tcdA is a potential epidemic strain in China.

Authors:  Pengcheng Du; Bo Cao; Jing Wang; Wenge Li; Hongbing Jia; Wen Zhang; Jinxing Lu; Zhongjie Li; Hongjie Yu; Chen Chen; Ying Cheng
Journal:  J Clin Microbiol       Date:  2014-06-23       Impact factor: 5.948

6.  Toxins, butyric acid, and other short-chain fatty acids are coordinately expressed and down-regulated by cysteine in Clostridium difficile.

Authors:  S Karlsson; A Lindberg; E Norin; L G Burman; T Akerlund
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

7.  Toxin gene analysis of a variant strain of Clostridium difficile that causes human clinical disease.

Authors:  S P Sambol; M M Merrigan; D Lyerly; D N Gerding; S Johnson
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

8.  Immunoblots and plasmid fingerprints compared with serotyping and polyacrylamide gel electrophoresis for typing Clostridium difficile.

Authors:  M E Mulligan; L R Peterson; R Y Kwok; C R Clabots; D N Gerding
Journal:  J Clin Microbiol       Date:  1988-01       Impact factor: 5.948

9.  Proline-dependent regulation of Clostridium difficile Stickland metabolism.

Authors:  Laurent Bouillaut; William T Self; Abraham L Sonenshein
Journal:  J Bacteriol       Date:  2012-12-07       Impact factor: 3.490

10.  Effect of various diets on toxin production by two strains of Clostridium difficile in gnotobiotic mice.

Authors:  S Mahe; G Corthier; F Dubos
Journal:  Infect Immun       Date:  1987-08       Impact factor: 3.441

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