A Jakubczyk1, J Skrzeszewski1, E M Trucco2, H Suszek3, J Zaorska1, M Nowakowska1, A Michalska1, M Wojnar4, M Kopera5. 1. Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland. 2. Department of Psychology and the Center for Children and Families, Florida International University, Miami, FL, 33199, USA; Department of Psychiatry, Addiction Center, University of Michigan, Ann Arbor, MI, 48109, USA. 3. Department of Psychology, University of Warsaw, Warsaw, Poland. 4. Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland; Department of Psychiatry, Addiction Center, University of Michigan, Ann Arbor, MI, 48109, USA. 5. Department of Psychiatry, Medical University of Warsaw, Warsaw, Poland. Electronic address: maciej.kopera@wum.edu.pl.
Abstract
BACKGROUND: Interoception may contribute to substance use disorder as it relates to the body's experience of substance use or withdrawal. However, only a few studies have directly investigated associations between interoception and alcohol use. The objective of this study was to compare individuals with alcohol use disorder (AUD) and healthy controls on interoceptive sensibility and accuracy. METHODS: The sample was comprised of two groups: individuals meeting criteria for AUD (N = 114) and healthy controls (N = 110) not meeting criteria for AUD. Interoceptive sensibility was assessed with a self-report measure (the Private Body Consciousness subscale) and interoceptive accuracy - with a behavioral measure (the Schandry test). In addition, associations between interoception and other well-recognized correlates of AUD (sleep problems, depressive and anxiety symptoms, impulsivity) were tested. Barratt's Impulsiveness Scale, Brief Symptom Inventory, and Athens Insomnia Scale were utilized to assess psychopathological symptoms as covariates. RESULTS: When controlling for level of anxiety, sleep problems, age, sex and education, individuals with AUD scored significantly higher on self-reported interoceptive sensibility and lower on interoceptive accuracy in comparison to healthy controls. Higher interoceptive sensibility was associated with more severe sleep problems and anxiety symptoms. CONCLUSIONS: These results have to be treated as preliminary and need to be replicated; however, findings indicate that interoception may present a novel therapeutic target for treatment of AUD.
BACKGROUND: Interoception may contribute to substance use disorder as it relates to the body's experience of substance use or withdrawal. However, only a few studies have directly investigated associations between interoception and alcohol use. The objective of this study was to compare individuals with alcohol use disorder (AUD) and healthy controls on interoceptive sensibility and accuracy. METHODS: The sample was comprised of two groups: individuals meeting criteria for AUD (N = 114) and healthy controls (N = 110) not meeting criteria for AUD. Interoceptive sensibility was assessed with a self-report measure (the Private Body Consciousness subscale) and interoceptive accuracy - with a behavioral measure (the Schandry test). In addition, associations between interoception and other well-recognized correlates of AUD (sleep problems, depressive and anxiety symptoms, impulsivity) were tested. Barratt's Impulsiveness Scale, Brief Symptom Inventory, and Athens Insomnia Scale were utilized to assess psychopathological symptoms as covariates. RESULTS: When controlling for level of anxiety, sleep problems, age, sex and education, individuals with AUD scored significantly higher on self-reported interoceptive sensibility and lower on interoceptive accuracy in comparison to healthy controls. Higher interoceptive sensibility was associated with more severe sleep problems and anxiety symptoms. CONCLUSIONS: These results have to be treated as preliminary and need to be replicated; however, findings indicate that interoception may present a novel therapeutic target for treatment of AUD.
Authors: Donna L Ewing; Miranda Manassei; Cassandra Gould van Praag; Andrew O Philippides; Hugo D Critchley; Sarah N Garfinkel Journal: Biol Psychol Date: 2017-05-26 Impact factor: 3.251
Authors: Ryan Smith; Justin S Feinstein; Rayus Kuplicki; Katherine L Forthman; Jennifer L Stewart; Martin P Paulus; Sahib S Khalsa Journal: Sci Rep Date: 2021-01-22 Impact factor: 4.996
Authors: Paweł Wiśniewski; Pierre Maurage; Andrzej Jakubczyk; Elisa M Trucco; Hubert Suszek; Maciej Kopera Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 2021-07-03 Impact factor: 5.067
Authors: Andrzej Jakubczyk; Elisa M Trucco; Anna Klimkiewicz; Jakub Skrzeszewski; Hubert Suszek; Justyna Zaorska; Malwina Nowakowska; Aneta Michalska; Marcin Wojnar; Maciej Kopera Journal: Front Psychiatry Date: 2020-02-03 Impact factor: 4.157
Authors: Justyna Zaorska; Maciej Kopera; Elisa M Trucco; Hubert Suszek; Paweł Kobyliński; Andrzej Jakubczyk Journal: Front Psychiatry Date: 2020-10-30 Impact factor: 4.157