Literature DB >> 3087260

Rheological properties of middle ear effusions from children with otitis media with effusion.

Y Majima, Y Sakakura, T Matsubara, Y Hamaguchi, K Hirata, K Takeuchi, Y Miyoshi.   

Abstract

Freshly harvested middle ear effusions (MEE) were collected from children with otitis media with effusion. Both elasticity (G') and viscosity (eta') of the MEE were determined by an oscillating sphere magnetic rheometer and compared with transportability of the MEE on mucus-depleted frog palates. A maximum value of transport was obtained at G' of about 20 dyne/cm2 (at 1 Hz), and below this value there was a significant positive correlation between the transport rate and log G'. Above 20 dyne/cm2, the negative correlation between the transport rate and log G' was significant. This shows there is a sharp increase in transport with increase in G' up to 20 dyne/cm2, and at the higher value of G' there is a slow decrease in transport with increasing G'. A similar significant correlation between the transport rate and log eta' was observed.

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Year:  1986        PMID: 3087260     DOI: 10.1177/00034894860950s301

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol Suppl        ISSN: 0096-8056


  8 in total

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Authors:  N G Schipper; J C Verhoef; F W Merkus
Journal:  Pharm Res       Date:  1991-07       Impact factor: 4.200

2.  The effect of middle ear effusions from children on in vitro ciliary activity.

Authors:  K Takeuchi; S Saida; Y Majima; Y Sakakura
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

3.  Viscoelastic properties of middle ear effusions from pediatric otitis media with effusion and their relation to gross appearance.

Authors:  K Takeuchi; Y Majima; K Hirata; A Morishita; M Hattori; Y Sakakura
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

4.  Biochemical and cytological studies of immune-complex-induced otitis media in the chinchilla.

Authors:  Y Hamaguchi; S K Juhn; Y Sakakura
Journal:  Arch Otorhinolaryngol       Date:  1988

5.  The effect of an orally administered proteolytic enzyme on the elasticity and viscosity of nasal mucus.

Authors:  Y Majima; M Inagaki; K Hirata; K Takeuchi; A Morishita; Y Sakakura
Journal:  Arch Otorhinolaryngol       Date:  1988

6.  Rheological characterization of neutral and anionic polysaccharides with reduced mucociliary transport rates.

Authors:  Ankur J Shah; Maureen D Donovan
Journal:  AAPS PharmSciTech       Date:  2007-04-20       Impact factor: 3.246

7.  Formulating gels for decreased mucociliary transport using rheologic properties: polyacrylic acids.

Authors:  Ankur J Shah; Maureen D Donovan
Journal:  AAPS PharmSciTech       Date:  2007-04-20       Impact factor: 3.246

8.  The role of inflammatory mediators in the pathogenesis of otitis media and sequelae.

Authors:  Steven K Juhn; Min-Kyo Jung; Mark D Hoffman; Brian R Drew; Diego A Preciado; Nicholas J Sausen; Timothy T K Jung; Bo Hyung Kim; Sang-Yoo Park; Jizhen Lin; Frank G Ondrey; David R Mains; Tina Huang
Journal:  Clin Exp Otorhinolaryngol       Date:  2008-09-30       Impact factor: 3.372

  8 in total

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