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Literature DB >> 2393565

The effect of middle ear effusions from children on in vitro ciliary activity.

K Takeuchi¹, S Saida, Y Majima, Y Sakakura.

Abstract

In an attempt to clarify the effect of middle ear effusions (MEEs) on ciliary activity, the ciliary beat frequency (CBF) of nasal epithelium from normal subjects was determined following incubation in Hanks' solution containing effusions from pediatric otitis media with effusion. Both serous and mucoid types of effusions increased CBF 15 min after incubation. The mucoid type of effusion was then found to decrease CBF 6 h after incubation. Since the pH and osmotic pressure of the solution containing the effusions were within the physiological ranges for normal ciliary beating, our findings show that MEEs can influence CBF in vitro.

Entities: Chemical Disease Species

Mesh：

Year: 1990 PMID： 2393565 DOI： 10.1007/bf00176546

Source DB: PubMed Journal: Eur Arch Otorhinolaryngol ISSN： 0937-4477 Impact factor: 2.503

20 in total

1. Prostaglandins in human middle ear effusions.

Authors: R T Jackson; M B Waitzman; L Pickford; S E Nathanson
Journal: Prostaglandins Date: 1975-08

2. Action of inflammatory mediators on middle ear mucosa. A method for measuring permeability and swelling.

Authors: R G Dennis; R N Whitmire; R T Jackson
Journal: Arch Otolaryngol Date: 1976-07

3. Functional disorder of eustachian tube in experimental otitis media with effusion following inoculation of bacterial endotoxin.

Authors: Y Ohashi; Y Nakai; H Ikeoka; H Koshimo; Y Esaki; S Kato; M Kato
Journal: Ann Otol Rhinol Laryngol Date: 1988 Jul-Aug Impact factor: 1.547

The effect of middle ear effusions from children on in vitro ciliary activity.

1. Prostaglandins in human middle ear effusions.

2. Action of inflammatory mediators on middle ear mucosa. A method for measuring permeability and swelling.

3. Functional disorder of eustachian tube in experimental otitis media with effusion following inoculation of bacterial endotoxin.

4. Kinetics of lysosomal protease activity in human otitis media with effusion.

5. Effect of a toxin produced by Haemophilus influenzae on ciliated respiratory epithelium.

6. Factors influencing the mucociliary activity in the respiratory tract. A review.

7. Effect of pH, viscosity and ionic-strength changes on ciliary beating frequency of human bronchial explants.

8. Endotoxin in middle ear effusions tested with Limulus assay.

9. Mucociliary function in children with secretory otitis media.

10. Effects of bacterial endotoxin on ciliary activity in the tubotympanum.

1. The ciliary beat frequency of middle ear mucosa in children with chronic secretory otitis media.

Review 2. What have we learned from murine models of otitis media?

3. Non-invasive optical assessment of viscosity of middle ear effusions in otitis media.