Literature DB >> 3086866

Sequence analysis and structure-function correlations of murine q, k, u, s, and f haplotype I-A beta cDNA clones.

P Estess, A B Begovich, M Koo, P P Jones, H O McDevitt.   

Abstract

I-A beta-chain cDNA clones from mice of the q, k, u, s, and f haplotypes have been isolated and sequenced. Nucleotide sequence comparisons among these five A beta chains show considerable allelic variation in the region encoding the first external (beta 1) domain of the mature A beta protein. The beta 1 domain variability is clustered into three discrete regions, two of which divide the A beta chains into subgroups, suggesting an evolutionary history for the separation of alleles in inbred strains of mice. The amino acid sequences of these five chains are compared to each other and to previously published I-A beta chains. Correlations are made between the primary structural differences and the serologic and immune response characteristics mapping to the I-A subregion.

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Year:  1986        PMID: 3086866      PMCID: PMC323569          DOI: 10.1073/pnas.83.11.3594

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  42 in total

1.  Genetic control of the immune response. Relationship between the immune response-1 gene(s) and individual H-2 antigenic specificities.

Authors:  F C Grumet; H O McDevitt
Journal:  Transplantation       Date:  1972-02       Impact factor: 4.939

2.  Influence of allelic polymorphism on the assembly and surface expression of class II MHC (Ia) molecules.

Authors:  R N Germain; D M Bentley; H Quill
Journal:  Cell       Date:  1985-11       Impact factor: 41.582

3.  Genetic control of the immune response to myoglobins. IV. Inhibition of determinant-specific Ir gene-controlled antigen presentation and induction of suppression by pretreatment of presenting cells with anti-Ia antibodies.

Authors:  J A Berzofsky; L K Richman
Journal:  J Immunol       Date:  1981-05       Impact factor: 5.422

4.  Interaction between I region loci influences the expression of a cell surface Ia antigen.

Authors:  D B Murphy; P P Jones; M R Loken; H O McDevitt
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

5.  Definitive mapping of the immune response gene(s) for (T,G)-A--L to the I-A subregion.

Authors:  M Markman; H B Dickler
Journal:  J Immunol       Date:  1980-06       Impact factor: 5.422

Review 6.  The traditional and a new version of the mouse H-2 complex.

Authors:  J Klein; A Juretic; C N Baxevanis; Z A Nagy
Journal:  Nature       Date:  1981-06-11       Impact factor: 49.962

7.  Genetic control of the immune response. Mapping of the Ir-1 locus.

Authors:  H O McDevitt; B D Deak; D C Shreffler; J Klein; J H Stimpfling; G D Snell
Journal:  J Exp Med       Date:  1972-06-01       Impact factor: 14.307

8.  Encephalitogenic T cell clones specific for myelin basic protein. An unusual bias in antigen recognition.

Authors:  S S Zamvil; P A Nelson; D J Mitchell; R L Knobler; R B Fritz; L Steinman
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307

9.  Expression of a single major histocompatibility complex locus controls the immune response to poly-L-(tyrosine, glutamic acid)-poly-DL-alanine-poly-L-lysine.

Authors:  B D Deak; D Meruelo; H O McDevitt
Journal:  J Exp Med       Date:  1978-02-01       Impact factor: 14.307

10.  Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.

Authors:  J W Kappler; B Skidmore; J White; P Marrack
Journal:  J Exp Med       Date:  1981-05-01       Impact factor: 14.307

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  40 in total

1.  Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells.

Authors:  S Ikehara; M Kawamura; F Takao; M Inaba; R Yasumizu; S Than; H Hisha; K Sugiura; Y Koide; T O Yoshida
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

Review 2.  Multiple sclerosis and its animal models: the role of the major histocompatibility complex and the T cell receptor repertoire.

Authors:  L Steinman
Journal:  Springer Semin Immunopathol       Date:  1992

3.  Point mutations define positions in HLA-DR3 molecules that affect antigen presentation.

Authors:  E Mellins; B Arp; D Singh; B Carreno; L Smith; A H Johnson; D Pious
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

4.  Evolution of major histocompatibility complex class II allelic diversity: direct descent in mice and humans.

Authors:  A S Lundberg; H O McDevitt
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

Review 5.  Mapping T cell receptor epitopes on the A beta polypeptide.

Authors:  B N Beck; D J McKean
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

6.  DNase I hypersensitive sites flank the mouse class II major histocompatibility complex during B cell development.

Authors:  S Carson
Journal:  Nucleic Acids Res       Date:  1991-09-25       Impact factor: 16.971

7.  Structure function analysis of the H-2 Abp gene.

Authors:  J A Harton; W Litaker; J A Frelinger; G A Bishop
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

Review 8.  Ancestral polymorphisms of MHC class II genes: divergent allele advantage.

Authors:  E K Wakeland; S Boehme; J X She; C C Lu; R A McIndoe; I Cheng; Y Ye; W K Potts
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

Review 9.  Evolution of class II genes: role of selection in both the maintenance of polymorphism and the retention of non-expressed alleles.

Authors:  P P Jones; A B Begovich; F M Tacchini-Cottier; T H Vu
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

10.  Nucleotide sequence analysis of MHC class II genes in autoimmune disease-prone (NZB x NZW)F1 mice.

Authors:  S Ogawa; H Nishimura; M Awaji; S Nozawa; S Hirose; T Shirai
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

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