Literature DB >> 30867309

In Vivo Models of Oncoproteins Encoded by Kaposi's Sarcoma-Associated Herpesvirus.

Ariana G Bravo Cruz1, Blossom Damania2.   

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) is a human oncogenic virus. KSHV utilizes its proteins to modify the cellular environment to promote viral replication and persistence. Some of these proteins are oncogenic, modulating cell proliferation, apoptosis, angiogenesis, genome stability, and immune responses, among other cancer hallmarks. These changes can lead to the development of KSHV-associated malignancies. In this Gem, we focus on animal models of oncogenic KSHV proteins that were developed to enable better understanding of KSHV tumorigenesis.
Copyright © 2019 American Society for Microbiology.

Entities:  

Keywords:  KS; Kaposi’s sarcoma-associated herpesvirus; MCD; PEL; animal models; lymphoma

Mesh：

Substances：

Year:  2019        PMID： 30867309      PMCID： PMC6532075          DOI： 10.1128/JVI.01053-18

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  115 in total

1.  Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6.

Authors:  Y Aoki; E S Jaffe; Y Chang; K Jones; J Teruya-Feldstein; P S Moore; G Tosato
Journal:  Blood       Date:  1999-06-15       Impact factor: 22.113

2.  p53 inhibition by the LANA protein of KSHV protects against cell death.

Authors:  J Friborg; W Kong; M O Hottiger; G J Nabel
Journal:  Nature       Date:  1999 Dec 23-30       Impact factor: 49.962

3.  Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus.

Authors:  M Lagunoff; R Majeti; A Weiss; D Ganem
Journal:  Proc Natl Acad Sci U S A       Date:  1999-05-11       Impact factor: 11.205

4.  Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen.

Authors:  M E Ballestas; P A Chatis; K M Kaye
Journal:  Science       Date:  1999-04-23       Impact factor: 47.728

5.  Transcriptional analysis of human herpesvirus-8 open reading frames 71, 72, 73, K14, and 74 in a primary effusion lymphoma cell line.

Authors:  S J Talbot; R A Weiss; P Kellam; C Boshoff
Journal:  Virology       Date:  1999-04-25       Impact factor: 3.616

6.  The latency-associated nuclear antigen tethers the Kaposi's sarcoma-associated herpesvirus genome to host chromosomes in body cavity-based lymphoma cells.

Authors:  M A Cotter; E S Robertson
Journal:  Virology       Date:  1999-11-25       Impact factor: 3.616

7.  Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins.

Authors:  P M Chaudhary; A Jasmin; M T Eby; L Hood
Journal:  Oncogene       Date:  1999-10-14       Impact factor: 9.867

8.  Expression of K13/v-FLIP gene of human herpesvirus 8 and apoptosis in Kaposi's sarcoma spindle cells.

Authors:  M Stürzl; C Hohenadl; C Zietz; E Castanos-Velez; A Wunderlich; G Ascherl; P Biberfeld; P Monini; P J Browning; B Ensoli
Journal:  J Natl Cancer Inst       Date:  1999-10-20       Impact factor: 13.506

9.  Kaposi's sarcoma-associated herpesvirus-encoded v-cyclin triggers apoptosis in cells with high levels of cyclin-dependent kinase 6.

Authors:  P M Ojala; M Tiainen; P Salven; T Veikkola; E Castaños-Vélez; R Sarid; P Biberfeld; T P Mäkelä
Journal:  Cancer Res       Date:  1999-10-01       Impact factor: 12.701

10.  Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma.

Authors:  T Y Yang; S C Chen; M W Leach; D Manfra; B Homey; M Wiekowski; L Sullivan; C H Jenh; S K Narula; S W Chensue; S A Lira
Journal:  J Exp Med       Date:  2000-02-07       Impact factor: 14.307
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  5 in total

Review 1.  Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire.

Authors:  Monika A Zelazowska; Kevin McBride; Laurie T Krug
Journal:  Viruses       Date:  2020-07-23       Impact factor: 5.048

2.  Gammaherpesvirus-infected germinal center cells express a distinct immunoglobulin repertoire.

Authors:  Monika A Zelazowska; Qiwen Dong; Joshua B Plummer; Yi Zhong; Bin Liu; Laurie T Krug; Kevin M McBride
Journal:  Life Sci Alliance       Date:  2020-02-06

3.  Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis.

Authors:  Salum J Lidenge; Andrew V Kossenkov; For Yue Tso; Jayamanna Wickramasinghe; Sara R Privatt; Owen Ngalamika; John R Ngowi; Julius Mwaiselage; Paul M Lieberman; John T West; Charles Wood
Journal:  PLoS Pathog       Date:  2020-07-24       Impact factor: 6.823

4.  A Panel of Kaposi's Sarcoma-Associated Herpesvirus Mutants in the Polycistronic Kaposin Locus for Precise Analysis of Individual Protein Products.

Authors:  Mariel Kleer; Grant MacNeil; Nancy Adam; Eric S Pringle; Jennifer A Corcoran
Journal:  J Virol       Date:  2021-12-22       Impact factor: 5.103

5.  Murine Models of Chronic Viral Infections and Associated Cancers.

Authors:  D V Avdoshina; A S Kondrashova; M G Belikova; E O Bayurova
Journal:  Mol Biol       Date:  2022-10-05       Impact factor: 1.540
  5 in total

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