Literature DB >> 30865805

Human Genetics and Drug Development.

Michael V Holmes1.   

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Year:  2019        PMID： 30865805     DOI： 10.1056/NEJMe1901565

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


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  11 in total

Review 1.  Stroke Genetics: Turning Discoveries into Clinical Applications.

Authors:  Martin Dichgans; Nathalie Beaufort; Stephanie Debette; Christopher D Anderson
Journal:  Stroke       Date:  2021-08-17       Impact factor: 10.170

2.  Metabolism, Obesity, and Diabetes Mellitus.

Authors:  Henry H Ruiz; Raquel López Díez; Lakshmi Arivazahagan; Ravichandran Ramasamy; Ann Marie Schmidt
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-06-26       Impact factor: 8.311

3.  Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics.

Authors:  Jonas Bovijn; Kristi Krebs; Chia-Yen Chen; Ruth Boxall; Jenny C Censin; Teresa Ferreira; Sara L Pulit; Craig A Glastonbury; Samantha Laber; Iona Y Millwood; Kuang Lin; Liming Li; Zhengming Chen; Lili Milani; George Davey Smith; Robin G Walters; Reedik Mägi; Benjamin M Neale; Cecilia M Lindgren; Michael V Holmes
Journal:  Sci Transl Med       Date:  2020-06-24       Impact factor: 17.956

Review 4.  Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development.

Authors:  Michael V Holmes; Tom G Richardson; Brian A Ference; Neil M Davies; George Davey Smith
Journal:  Nat Rev Cardiol       Date:  2021-03-11       Impact factor: 32.419

5.  Commentary: Big data bring big controversies: HDL cholesterol and mortality.

Authors:  Mika Ala-Korpela; Sanna Kuusisto; Michael V Holmes
Journal:  Int J Epidemiol       Date:  2021-07-09       Impact factor: 7.196

6.  Rethinking the combination treatment of fulvestrant and anastrozole for metastatic breast cancer: an integrated reanalysis of aromatase-estrogen receptor axis.

Authors:  Xing Huang
Journal:  Clin Transl Med       Date:  2019-11-18

7.  PCSK9 genetic variants and cognitive abilities: a large-scale Mendelian randomization study.

Authors:  Donald M Lyall; Joey Ward; Maciej Banach; George Davey Smith; Jason G Gill; Jill P Pell; Michael V Holmes; Naveed Sattar
Journal:  Arch Med Sci       Date:  2021-01-05       Impact factor: 3.318

8.  Commentary: Using human genetics to guide the repurposing of medicines.

Authors:  Jonas Bovijn; Jenny C Censin; Cecilia M Lindgren; Michael V Holmes
Journal:  Int J Epidemiol       Date:  2020-08-01       Impact factor: 7.196

Review 9.  Kidney disease trials for the 21st century: innovations in design and conduct.

Authors:  William G Herrington; Natalie Staplin; Richard Haynes
Journal:  Nat Rev Nephrol       Date:  2019-10-31       Impact factor: 28.314

10.  Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.

Authors:  Tom G Richardson; Eleanor Sanderson; Tom M Palmer; Mika Ala-Korpela; Brian A Ference; George Davey Smith; Michael V Holmes
Journal:  PLoS Med       Date:  2020-03-23       Impact factor: 11.069
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