| Literature DB >> 30864508 |
Catalina Bazacliu1, Josef Neu1.
Abstract
Necrotizing enterocolitis (NEC) remains the most threatening gastrointestinal complication of prematurity leading to high mortality, morbidity and cost. Common complications of NEC include neurodevelopmental delay, failure to thrive, gastrointestinal problems including strictures and adhesions, cholestasis, short bowel syndrome with or without intestinal failure that can be difficult to manage. Infants who develop NEC benefit from close follow-up for early diagnosis and treatment of complications. Those who present with severe complications such as intestinal failure benefit from a multidisciplinary approach involving careful assessment and treatment. Studies done so far are limited in providing a long-term prognosis. Here we review some of these complications. More studies with a longer follow-up period are needed to better understand the later comorbidities that develop in babies with NEC. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Necrotizing enterocolitis; adhesions; cholestasis; complications; intestinal failure; spontaneous intestinal perforation.
Mesh:
Year: 2019 PMID: 30864508 DOI: 10.2174/1573396315666190312093119
Source DB: PubMed Journal: Curr Pediatr Rev ISSN: 1573-3963