Literature DB >> 30859383

Molecular-Physiological Aspects of Regulatory Effect of Peptide Retinoprotectors.

V Khavinson1,2, S Trofimova1, A Trofimov1, I Solomin3.   

Abstract

Retinal diseases were always difficult problem for clinical ophthalmology. Modern methods of their treatment only decrease risk of complications, however in Russia was created better technology for this purpose: peptide bioregulators, which were made by sequential adding of amino acids one to another, binding with the promoter region of genes, and promoting retinoprotective effect by regulation of their expression, improving the state of the retina.

Entities:  

Keywords:  Binding sites; DNA; Peptide bioregulators; Promoter regions; Retinal diseases; Short peptides

Mesh：

Substances：

Year:  2019        PMID： 30859383     DOI： 10.1007/s12015-019-09882-7

Source DB:  PubMed          Journal:  Stem Cell Rev Rep        ISSN： 2629-3277            Impact factor:   5.739


  23 in total

1.  Pineal-regulating tetrapeptide epitalon improves eye retina condition in retinitis pigmentosa.

Authors:  Vladimir Khavinson; Michael Razumovsky; Svetlana Trofimova; Roman Grigorian; Anna Razumovskaya
Journal:  Neuro Endocrinol Lett       Date:  2002-08       Impact factor: 0.765

2.  Retinoprotective effect of Epithalon in campbell rats of various ages.

Authors:  V Kh Khavinson; M I Razumovsky; S V Trofimova; A M Razumovskaya
Journal:  Bull Exp Biol Med       Date:  2003-05       Impact factor: 0.804

3.  Effects of peptides on proliferative activity of retinal and pigmented epithelial cells.

Authors:  V Kh Khavinson; V N Zemchikhina; S V Trofimova; V V Malinin
Journal:  Bull Exp Biol Med       Date:  2003-06       Impact factor: 0.804

4.  Site-specific binding of short peptides with DNA modulated eukaryotic endonuclease activity.

Authors:  V Kh Khavinson; L I Fedoreyeva; B F Vanyushin
Journal:  Bull Exp Biol Med       Date:  2011-05       Impact factor: 0.804

5.  Short peptides modulate the effect of endonucleases of wheat seedling.

Authors:  V Kh Khavinson; L I Fedoreeva; B F Vanyushin
Journal:  Dokl Biochem Biophys       Date:  2011-05-18       Impact factor: 0.788

6.  A method of creation a cell monolayer based on organotypic culture for screening of physiologically active substances.

Authors:  V Kh Khavinson; N S Linkova; V E Pronyaeva; N I Chalisova; E A Koncevaya; V O Polyakova; T V Kvetnaya; I M Kvetnoy; G M Yakovlev
Journal:  Bull Exp Biol Med       Date:  2012-09       Impact factor: 0.804

7.  The peptides ADNF-9 and NAP increase survival and neurite outgrowth of rat retinal ganglion cells in vitro.

Authors:  Wolf A Lagrèze; Amelie Pielen; Ruth Steingart; Günther Schlunck; Hans-Dieter Hofmann; Illana Gozes; Matthias Kirsch
Journal:  Invest Ophthalmol Vis Sci       Date:  2005-03       Impact factor: 4.799

8.  Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA.

Authors:  L I Fedoreyeva; I I Kireev; V Kh Khavinson; B F Vanyushin
Journal:  Biochemistry (Mosc)       Date:  2011-11       Impact factor: 2.487

9.  Ocular complications after anti-vascular endothelial growth factor therapy in Medicare patients with age-related macular degeneration.

Authors:  Shelley Day; Kofi Acquah; Prithvi Mruthyunjaya; Daniel S Grossman; Paul P Lee; Frank A Sloan
Journal:  Am J Ophthalmol       Date:  2011-06-12       Impact factor: 5.258

Review 10.  Functional aspects of the somatostatinergic system in the retina and the potential therapeutic role of somatostatin in retinal disease.

Authors:  G Casini; E Catalani; M Dal Monte; P Bagnoli
Journal:  Histol Histopathol       Date:  2005-04       Impact factor: 2.303
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  1 in total

Review 1.  Peptide Regulation of Cell Differentiation.

Authors:  Vladimir Khavinson; Natalia Linkova; Anastasiia Diatlova; Svetlana Trofimova
Journal:  Stem Cell Rev Rep       Date:  2020-02       Impact factor: 5.739
  1 in total

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