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Literature DB >> 30858551

Degradation of Bruton's tyrosine kinase mutants by PROTACs for potential treatment of ibrutinib-resistant non-Hodgkin lymphomas.

Yonghui Sun¹, Ning Ding², Yuqin Song², Zimo Yang¹, Wanli Liu³, Jun Zhu⁴, Yu Rao⁵.

Abstract

Entities: Chemical Disease

Mesh：

Substances：

Year: 2019 PMID： 30858551 DOI： 10.1038/s41375-019-0440-x

Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528

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Cited

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33 in total

Review 1. PROTACs: great opportunities for academia and industry.

Authors: Xiuyun Sun; Hongying Gao; Yiqing Yang; Ming He; Yue Wu; Yugang Song; Yan Tong; Yu Rao
Journal: Signal Transduct Target Ther Date: 2019-12-24

2. PROTAC Technology: Opportunities and Challenges.

Authors: Hongying Gao; Xiuyun Sun; Yu Rao
Journal: ACS Med Chem Lett Date: 2020-03-12 Impact factor: 4.345

Review 3. Recent Developments in PROTAC-Mediated Protein Degradation: From Bench to Clinic.

Authors: Zhenyi Hu; Craig M Crews
Journal: Chembiochem Date: 2021-09-23 Impact factor: 3.461

4. Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently.

Authors: Zimo Yang; Yonghui Sun; Zhihao Ni; Celi Yang; Yan Tong; Yujie Liu; Haitao Li; Yu Rao
Journal: Cell Res Date: 2021-08-20 Impact factor: 46.297

Review 5. PROTACs: great opportunities for academia and industry (an update from 2020 to 2021).

Authors: Ming He; Chaoguo Cao; Zhihao Ni; Yongbo Liu; Peilu Song; Shuang Hao; Yuna He; Xiuyun Sun; Yu Rao
Journal: Signal Transduct Target Ther Date: 2022-06-09

6. Discovery and resistance mechanism of a selective CDK12 degrader.

Authors: Baishan Jiang; Yang Gao; Jianwei Che; Wenchao Lu; Ines H Kaltheuner; Ruben Dries; Marian Kalocsay; Matthew J Berberich; Jie Jiang; Inchul You; Nicholas Kwiatkowski; Kristin M Riching; Danette L Daniels; Peter K Sorger; Matthias Geyer; Tinghu Zhang; Nathanael S Gray
Journal: Nat Chem Biol Date: 2021-03-22 Impact factor: 15.040

Degradation of Bruton's tyrosine kinase mutants by PROTACs for potential treatment of ibrutinib-resistant non-Hodgkin lymphomas.

Review 1. PROTACs: great opportunities for academia and industry.

2. PROTAC Technology: Opportunities and Challenges.

Review 3. Recent Developments in PROTAC-Mediated Protein Degradation: From Bench to Clinic.

4. Merging PROTAC and molecular glue for degrading BTK and GSPT1 proteins concurrently.

Review 5. PROTACs: great opportunities for academia and industry (an update from 2020 to 2021).

6. Discovery and resistance mechanism of a selective CDK12 degrader.

Review 7. Advancing targeted protein degradation for cancer therapy.

Review 8. E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points.

Review 9. Targeting Protein Kinases Degradation by PROTACs.

Review 10. Opportunities and Challenges of Small Molecule Induced Targeted Protein Degradation.