Literature DB >> 30844857

Targeting proprotein convertase subtilisin/kexin type 9 in mice and monkeys.

Ya Wang1,2, Murong Ma1,3, Jian-An Wang2, Alan Daugherty1,3,4, Hong S Lu1,3,4.   

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Year:  2019        PMID: 30844857      PMCID: PMC6513310          DOI: 10.1097/MOL.0000000000000583

Source DB:  PubMed          Journal:  Curr Opin Lipidol        ISSN: 0957-9672            Impact factor:   4.776


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  15 in total

Review 1.  Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies-Statement From ATVB Council.

Authors:  Peggy Robinet; Dianna M Milewicz; Lisa A Cassis; Nicholas J Leeper; Hong S Lu; Jonathan D Smith
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-01-04       Impact factor: 8.311

Review 2.  Key aspects of PCSK9 inhibition beyond LDL lowering.

Authors:  Stéphane Ramin-Mangata; Valentin Blanchard; Gilles Lambert
Journal:  Curr Opin Lipidol       Date:  2018-12       Impact factor: 4.776

3.  In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.

Authors:  Alexandra C Chadwick; Xiao Wang; Kiran Musunuru
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-07-27       Impact factor: 8.311

4.  Induction of sustained hypercholesterolemia by single adeno-associated virus-mediated gene transfer of mutant hPCSK9.

Authors:  Marta Roche-Molina; David Sanz-Rosa; Francisco M Cruz; Jaime García-Prieto; Sergio López; Rocío Abia; Francisco J G Muriana; Valentín Fuster; Borja Ibáñez; Juan A Bernal
Journal:  Arterioscler Thromb Vasc Biol       Date:  2014-10-23       Impact factor: 8.311

Review 5.  Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases.

Authors:  Arthur P Arnold; Lisa A Cassis; Mansoureh Eghbali; Karen Reue; Kathryn Sandberg
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-03-09       Impact factor: 8.311

6.  Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.

Authors:  Hong Lu; Deborah A Howatt; Anju Balakrishnan; Mark J Graham; Adam E Mullick; Alan Daugherty
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-07-28       Impact factor: 8.311

Review 7.  Recommendation on Design, Execution, and Reporting of Animal Atherosclerosis Studies: A Scientific Statement From the American Heart Association.

Authors:  Alan Daugherty; Alan R Tall; Mat J A P Daemen; Erling Falk; Edward A Fisher; Guillermo García-Cardeña; Aldons J Lusis; A Phillip Owens; Michael E Rosenfeld; Renu Virmani
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-07-20       Impact factor: 8.311

Review 8.  PCSK9: a key modulator of cardiovascular health.

Authors:  Nabil G Seidah; Zuhier Awan; Michel Chrétien; Majambu Mbikay
Journal:  Circ Res       Date:  2014-03-14       Impact factor: 17.367

9.  A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification.

Authors:  Claudia Goettsch; Joshua D Hutcheson; Sumihiko Hagita; Maximillian A Rogers; Michael D Creager; Tan Pham; Jung Choi; Andrew K Mlynarchik; Brett Pieper; Mads Kjolby; Masanori Aikawa; Elena Aikawa
Journal:  Atherosclerosis       Date:  2016-06-09       Impact factor: 5.162

10.  Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation.

Authors:  Sandeep Kumar; Dong-Won Kang; Amir Rezvan; Hanjoong Jo
Journal:  Lab Invest       Date:  2017-05-15       Impact factor: 5.662

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  1 in total

1.  Liraglutide blocks the proliferation, migration and phenotypic switching of Homocysteine (Hcy)-induced vascular smooth muscle cells (VSMCs) by suppressing proprotein convertase subtilisin kexin9 (PCSK9)/ low-density lipoprotein receptor (LDLR).

Authors:  Jingquan Ji; Ming Feng; Xiaohong Niu; Xinyu Zhang; Yilei Wang
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

  1 in total

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