| Literature DB >> 30844397 |
John H Krystal1, Chadi G Abdallah2, Gerard Sanacora3, Dennis S Charney4, Ronald S Duman5.
Abstract
Ketamine is the first exemplar of a rapid-acting antidepressant with efficacy for treatment-resistant symptoms of mood disorders. Its discovery emerged from a reconceptualization of the biology of depression. Neurobiological insights into ketamine efficacy shed new light on the mechanisms underlying antidepressant efficacy. Published by Elsevier Inc.Entities:
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Year: 2019 PMID: 30844397 PMCID: PMC6560624 DOI: 10.1016/j.neuron.2019.02.005
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173