Literature DB >> 30839045

Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect.

Chathura S Abeywickrama1, Kaveesha J Wijesinghe, Robert V Stahelin, Yi Pang.   

Abstract

A series of pyrene-benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability.

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Year:  2019        PMID： 30839045      PMCID： PMC6446231          DOI： 10.1039/c9cc01068h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  27 in total

1.  Lysosomes in cell death.

Authors:  Maria Eugenia Guicciardi; Marcel Leist; Gregory J Gores
Journal:  Oncogene       Date:  2004-04-12       Impact factor: 9.867

2.  Two-photon fluorescent probes for acidic vesicles in live cells and tissue.

Authors:  Hwan Myung Kim; Myoung Jin An; Jin Hee Hong; Byeong Ha Jeong; Ohyun Kwon; Ju-Yong Hyon; Seok-Cheol Hong; Kyoung J Lee; Bong Rae Cho
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

Review 3.  Lysosomal membrane permeabilization in cell death.

Authors:  P Boya; G Kroemer
Journal:  Oncogene       Date:  2008-10-27       Impact factor: 9.867

Review 4.  Lysosomal involvement in cell death and cancer.

Authors:  Thomas Kirkegaard; Marja Jäättelä
Journal:  Biochim Biophys Acta       Date:  2008-10-02

5.  Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group.

Authors:  Hao Zhu; Jiangli Fan; Qunli Xu; Honglin Li; Jingyun Wang; Pan Gao; Xiaojun Peng
Journal:  Chem Commun (Camb)       Date:  2012-10-31       Impact factor: 6.222

Review 6.  Towards specific functions of lysosomal cysteine peptidases: phenotypes of mice deficient for cathepsin B or cathepsin L.

Authors:  T Reinheckel; J Deussing; W Roth; C Peters
Journal:  Biol Chem       Date:  2001-05       Impact factor: 3.915

7.  Neuronal loss and brain atrophy in mice lacking cathepsins B and L.

Authors:  Ute Felbor; Benedikt Kessler; Walther Mothes; Hans H Goebel; Hidde L Ploegh; Roderick T Bronson; Bjorn R Olsen
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-04       Impact factor: 11.205

8.  Fluorescence enhancement of pyrene chromophores induced by alkyl groups through σ-π conjugation: systematic synthesis of primary, secondary, and tertiary alkylated pyrenes at the 1, 3, 6, and 8 positions and their photophysical properties.

Authors:  Yosuke Niko; Susumu Kawauchi; Shun Otsu; Katsumi Tokumaru; Gen-ichi Konishi
Journal:  J Org Chem       Date:  2013-02-26       Impact factor: 4.354

Review 9.  Multiple cell death pathways as regulators of tumour initiation and progression.

Authors:  Marja Jäättelä
Journal:  Oncogene       Date:  2004-04-12       Impact factor: 9.867

10.  Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation.

Authors:  Kithiganahalli N Balaji; Norbert Schaschke; Werner Machleidt; Marta Catalfamo; Pierre A Henkart
Journal:  J Exp Med       Date:  2002-08-19       Impact factor: 14.307
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  5 in total

1.  Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference.

Authors:  Chathura S Abeywickrama; Kaveesha J Wijesinghe; Robert V Stahelin; Yi Pang
Journal:  Bioorg Chem       Date:  2019-07-24       Impact factor: 5.275

2.  Pyrene-Functionalized Fluorescent Nanojars: Synthesis, Mass Spectrometric, and Photophysical Studies.

Authors:  Melanie M Mitchell; Vageesha W Liyana Gunawardana; Guda Ramakrishna; Gellert Mezei
Journal:  ACS Omega       Date:  2021-11-22

Review 3.  Lighting up Individual Organelles With Fluorescent Carbon Dots.

Authors:  Haifang Liu; Jiancheng Guo; Aaron Albert Aryee; Linlin Hua; Yuanqiang Sun; Zhaohui Li; Jianbo Liu; Wenxue Tang
Journal:  Front Chem       Date:  2021-11-26       Impact factor: 5.221

Review 4.  Pyrene-Based AIE Active Materials for Bioimaging and Theranostics Applications.

Authors:  Muthaiah Shellaiah; Kien-Wen Sun
Journal:  Biosensors (Basel)       Date:  2022-07-21

5.  The Unexpected Selectivity Switching from Mitochondria to Lysosome in a D-π-A Cyanine Dye.

Authors:  Chathura S Abeywickrama; Hannah J Baumann; Keti A Bertman; Brian Corbin; Yi Pang
Journal:  Biosensors (Basel)       Date:  2022-07-10
  5 in total

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