Literature DB >> 23114612

Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group.

Hao Zhu1, Jiangli Fan, Qunli Xu, Honglin Li, Jingyun Wang, Pan Gao, Xiaojun Peng.   

Abstract

Rlyso, a highly selective and sensitive pH sensor, can stain lysosomes with a novel lysosome-locating group, methylcarbitol. Rlyso was successfully used to detect lysosomal pH changes during apoptosis or induced by chloroquine while avoiding the "alkalizing effect" on lysosomes of current lysosomal probes with nitrogen-containing sidechains.

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Year:  2012        PMID： 23114612     DOI： 10.1039/c2cc36785h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

1.  Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect.

Authors:  Chathura S Abeywickrama; Kaveesha J Wijesinghe; Robert V Stahelin; Yi Pang
Journal:  Chem Commun (Camb)       Date:  2019-03-19       Impact factor: 6.222

2.  Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes.

Authors:  Yahya Alqahtani; Shenggang Wang; Asim Najmi; Yue Huang; Xiangming Guan
Journal:  Anal Bioanal Chem       Date:  2019-08-26       Impact factor: 4.142

3.  Luminescent Probes for Sensitive Detection of pH Changes in Live Cells through Two Near-Infrared Luminescence Channels.

Authors:  Shuwei Zhang; Tzu-Ho Chen; Hsien-Ming Lee; Jianheng Bi; Avik Ghosh; Mingxi Fang; Zichen Qian; Fei Xie; Jon Ainsley; Christo Christov; Fen-Tair Luo; Feng Zhao; Haiying Liu
Journal:  ACS Sens       Date:  2017-07-17       Impact factor: 7.711

4.  Fluorescent Probes Based on π-Conjugation Modulation between Hemicyanine and Coumarin Moieties for Ratiometric Detection of pH Changes in Live Cells with Visible and Near-infrared Channels.

Authors:  Shuai Xia; Jianbo Wang; Jianheng Bi; Xiao Wang; Mingxi Fang; Tyler Phillips; Aslan May; Nathan Conner; Marina Tanasova; Fen-Tair Luo; Haiying Liu
Journal:  Sens Actuators B Chem       Date:  2018-02-25       Impact factor: 7.460

5.  Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference.

Authors:  Chathura S Abeywickrama; Kaveesha J Wijesinghe; Robert V Stahelin; Yi Pang
Journal:  Bioorg Chem       Date:  2019-07-24       Impact factor: 5.275

6.  Highly photostable wide-dynamic-range pH sensitive semiconducting polymer dots enabled by dendronizing the near-IR emitters.

Authors:  L Chen; L Wu; J Yu; C-T Kuo; T Jian; I-C Wu; Y Rong; D T Chiu
Journal:  Chem Sci       Date:  2017-09-04       Impact factor: 9.825

Review 7.  Exploring cells with targeted biosensors.

Authors:  Diana Pendin; Elisa Greotti; Konstantinos Lefkimmiatis; Tullio Pozzan
Journal:  J Gen Physiol       Date:  2016-12-27       Impact factor: 4.086

8.  Optically Robust and Biocompatible Mechanosensitive Upconverting Nanoparticles.

Authors:  Alice Lay; Olivia H Sheppard; Chris Siefe; Claire A McLellan; Randy D Mehlenbacher; Stefan Fischer; Miriam B Goodman; Jennifer A Dionne
Journal:  ACS Cent Sci       Date:  2019-07-09       Impact factor: 14.553

9.  A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues.

Authors:  Jiangli Fan; Zhichao Han; Yao Kang; Xiaojun Peng
Journal:  Sci Rep       Date:  2016-01-22       Impact factor: 4.379

10.  A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging.

Authors:  Yingzhong Zhu; Lufei Xiao; Meng Zhao; Jiazheng Zhou; Qiong Zhang; Hui Wang; Shengli Li; Hongping Zhou; Jieying Wu; Yupeng Tian
Journal:  Biomed Res Int       Date:  2015-10-12       Impact factor: 3.411
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