| Literature DB >> 30837109 |
Yu-Jing Huang1, Guang-Xian Nan2.
Abstract
Angiogenesis refers to new capillaries that sprout and remold from existing vessels. The mechanism of angiogenesis is very complex. Many factors promote angiogenesis in the body, and many factors inhibit angiogenesis. Angiogenesis is closely correlated to oxidative stress. Oxidative stress plays an important role in its positive feedback mechanism. Oxidative stress is defined as the imbalance of the internal oxidation system and antioxidant system, which is correlated to the cause and prognosis of many vascular diseases, and can be used as a biomarker for these diseases. At the same time, good regulation of oxidative stress can promote angiogenesis and tissue repair. Therefore, the present study summarizes the relationship between oxidative stress and angiogenesis, and new progress, and discusses the effect and mechanism of oxidative stress on angiogenesis.Entities:
Keywords: Angiogenesis; Mechanism; Oxidative stress; ROS; VEGF
Mesh:
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Year: 2019 PMID: 30837109 DOI: 10.1016/j.jocn.2019.02.019
Source DB: PubMed Journal: J Clin Neurosci ISSN: 0967-5868 Impact factor: 1.961