| Literature DB >> 30834983 |
Tomoaki Taguchi1, Yusuke Yanagi2, Koichiro Yoshimaru2, Xiu-Ying Zhang2, Toshiharu Matsuura2, Koichi Nakayama3, Eiji Kobayashi4, Haruyoshi Yamaza5, Kazuaki Nonaka5, Shouichi Ohga6, Takayoshi Yamaza7.
Abstract
Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.Entities:
Keywords: Biliary atresia; Dental pulp; Diaphragm; Mesenchymal stem cell; Primary teeth
Mesh:
Year: 2019 PMID: 30834983 DOI: 10.1007/s00595-019-01783-z
Source DB: PubMed Journal: Surg Today ISSN: 0941-1291 Impact factor: 2.549