Literature DB >> 3083204

The effect of aldose reductase and its inhibition on sugar cataract formation.

P F Kador, Y Akagi, J H Kinoshita.   

Abstract

Cataracts associated with diabetes and galactosemia are characterized by their rapid onset and bilateral appearance. These cataracts display similar morphology and histology and have common biochemical mechanisms initiating the cataractous processes. An understanding of these biochemical mechanisms have been aided both by the ability to reproduce these cataracts in various animal models and by the development of potent inhibitors of aldose reductase. This is a US government work. There are no restrictions on its use.

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Year:  1986        PMID： 3083204     DOI： 10.1016/0026-0495(86)90181-2

Source DB:  PubMed          Journal:  Metabolism        ISSN： 0026-0495            Impact factor:   8.694


  10 in total

1.  Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis.

Authors:  E Kubo; D P Singh; Y Akagi
Journal:  Diabetologia       Date:  2005-03-11       Impact factor: 10.122

2.  High-resolution magic angle spinning 1H NMR spectroscopy of metabolic changes in rabbit lens after treatment with dexamethasone combined with UVB exposure.

Authors:  Oddbjørn Saether; Oystein Risa; Jitka Cejková; Jostein Krane; Anna Midelfart
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-10-13       Impact factor: 3.117

3.  Abnormalities caused by carbohydrate alterations in Ibeta6-N-acetylglucosaminyltransferase-deficient mice.

Authors:  Guo-Yun Chen; Hisako Muramatsu; Mineo Kondo; Nobuyuki Kurosawa; Yozo Miyake; Naoki Takeda; Takashi Muramatsu
Journal:  Mol Cell Biol       Date:  2005-09       Impact factor: 4.272

4.  The complications of diabetes mellitus.

Authors:  W L Henry
Journal:  J Natl Med Assoc       Date:  1987-06       Impact factor: 1.798

Review 5.  Oxidative stress. Biochemistry and human disease.

Authors:  A Bast; R J Goris
Journal:  Pharm Weekbl Sci       Date:  1989-12-15

6.  Suggested mechanism for the selective excretion of glucosylated albumin. The effects of diabetes mellitus and aging on this process and the origins of diabetic microalbuminuria.

Authors:  A Kowluru; R Kowluru; M W Bitensky; E J Corwin; S S Solomon; J D Johnson
Journal:  J Exp Med       Date:  1987-11-01       Impact factor: 14.307

7.  Propolis, a Constituent of Honey, Inhibits the Development of Sugar Cataracts and High-Glucose-Induced Reactive Oxygen Species in Rat Lenses.

Authors:  Teppei Shibata; Shinsuke Shibata; Naoko Shibata; Etsuko Kiyokawa; Hiroshi Sasaki; Dhirendra P Singh; Eri Kubo
Journal:  J Ophthalmol       Date:  2016-05-08       Impact factor: 1.909

8.  Diosgenin, a Novel Aldose Reductase Inhibitor, Attenuates the Galactosemic Cataract in Rats.

Authors:  Lixia Ji; Lixia Cheng; Zhihong Yang
Journal:  J Diabetes Res       Date:  2017-09-05       Impact factor: 4.011

9.  Protective effect of caffeine against high sugar-induced transcription of microRNAs and consequent gene silencing: a study using lenses of galactosemic mice.

Authors:  Shambhu D Varma; Svitlana Kovtun
Journal:  Mol Vis       Date:  2013-02-25       Impact factor: 2.367

10.  Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract.

Authors:  Fumito Kanada; Yoshihiro Takamura; Seiji Miyake; Kazuma Kamata; Mayumi Inami; Masaru Inatani; Masaya Oki
Journal:  Sci Rep       Date:  2019-12-27       Impact factor: 4.379
  10 in total

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