| Literature DB >> 30825223 |
Yoshikuni Kawaguchi1, Heather A Lillemoe1, Jean-Nicolas Vauthey1.
Abstract
Colorectal liver metastases (CLM) are not always resectable at the time of diagnosis. An insufficient future liver remnant is a factor excluding patients from curative intent resection. To deal with this issue, two-stage hepatectomy was introduced approximately 20 years ago. It is a sequential treatment strategy for bilateral CLM, which consists of preoperative chemotherapy, portal vein embolization, and planned first and second liver resections. This study reviews current evidence supporting use of two-stage hepatectomy.Entities:
Keywords: colorectal liver metastasis; future liver remnant; portal vein embolization; two-stage hepatectomy
Mesh:
Substances:
Year: 2019 PMID: 30825223 PMCID: PMC6422720 DOI: 10.1002/jso.25430
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454