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Literature DB >> 3082299

Experimental induction of rheumatoid factor and joint lesions in rabbits after intravenous injections of killed bacteria.

A C Hanglow, C J Welsh, P Conn, J M Pitts, A Rampling, R R Coombs.

Abstract

Rabbits receiving repeated intravenous injections of killed bacteria (Escherichia coli or Bacillus subtilis) developed IgM rheumatoid factor which reacted with autologous heat-aggregated IgG. In addition, 5/7 'Old English' and 7/8 'Sandy Lop' rabbits receiving killed E. coli developed rheumatoid-like synovial lesions. 'Old English' rabbits developed lesions of a more severe nature. Three of eight 'Sandy Lop' rabbits injected with killed B. subtilis had high levels of rheumatoid factor but only mild joint lesions.

Entities: Disease Species

Mesh：

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Year: 1986 PMID： 3082299 PMCID： PMC1001815 DOI： 10.1136/ard.45.1.50

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

20 in total

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Journal: Arthritis Rheum Date: 1983-12

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Journal: Eur J Immunol Date: 1983-11 Impact factor: 5.532

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Journal: J Immunol Methods Date: 1981 Impact factor: 2.303

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Authors: D A Nemazee; V L Sato
Journal: J Exp Med Date: 1983-08-01 Impact factor: 14.307

3. Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein.

Authors: M F van den Broek; E J Hogervorst; M C Van Bruggen; W Van Eden; R van der Zee; W B van den Berg
Journal: J Exp Med Date: 1989-08-01 Impact factor: 14.307

3 in total