Literature DB >> 3081893

Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.

J D Robishaw, D W Russell, B A Harris, M D Smigel, A G Gilman.   

Abstract

A bovine adrenal cDNA clone encoding the entire alpha subunit of the GTP-binding regulatory protein that stimulates adenylate cyclase (Gs) was isolated and sequenced. This cDNA directed the synthesis of the larger, 52-kDa form of the polypeptide in COS cells, even though the clone appeared to encode a 46-kDa protein. Comparison of the deduced amino acid sequence of Gs alpha with the alpha subunit of another G protein, transducin, revealed striking homologies.

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Year:  1986        PMID： 3081893      PMCID： PMC323053          DOI： 10.1073/pnas.83.5.1251

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  40 in total

1.  Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

Authors:  S M Mumby; R A Kahn; D R Manning; A G Gilman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

2.  Expression of chimeric genes in the early region of SV40.

Authors:  M Horowitz; C L Cepko; P A Sharp
Journal:  J Mol Appl Genet       Date:  1983

3.  Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue.

Authors:  D J Capon; E Y Chen; A D Levinson; P H Seeburg; D V Goeddel
Journal:  Nature       Date:  1983-03-03       Impact factor: 49.962

4.  The regulatory components of adenylate cyclase and transducin. A family of structurally homologous guanine nucleotide-binding proteins.

Authors:  D R Manning; A G Gilman
Journal:  J Biol Chem       Date:  1983-06-10       Impact factor: 5.157

5.  Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene.

Authors:  J P McGrath; D J Capon; D H Smith; E Y Chen; P H Seeburg; D V Goeddel; A D Levinson
Journal:  Nature       Date:  1983 Aug 11-17       Impact factor: 49.962

6.  Establishing homologies in protein sequences.

Authors:  M O Dayhoff; W C Barker; L T Hunt
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

7.  The amino acid sequence of elongation factor Tu of Escherichia coli. The complete sequence.

Authors:  R A Laursen; J J L'Italien; S Nagarkatti; D L Miller
Journal:  J Biol Chem       Date:  1981-08-10       Impact factor: 5.157

8.  The nucleotide sequence of the cloned tufA gene of Escherichia coli.

Authors:  T Yokota; H Sugisaki; M Takanami; Y Kaziro
Journal:  Gene       Date:  1980-12       Impact factor: 3.688

9.  The regulatory component of adenylate cyclase. Purification and properties.

Authors:  P C Sternweis; J K Northup; M D Smigel; A G Gilman
Journal:  J Biol Chem       Date:  1981-11-25       Impact factor: 5.157

10.  A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

Authors:  H Okayama; P Berg
Journal:  Mol Cell Biol       Date:  1983-02       Impact factor: 4.272
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  34 in total

1.  Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers.

Authors:  Lutz Birnbaumer
Journal:  Biochim Biophys Acta       Date:  2006-12-15

2.  Selective G-protein regulation of neuronal calcium channels.

Authors:  P T Toth; L R Shekter; G H Ma; L H Philipson; R J Miller
Journal:  J Neurosci       Date:  1996-08-01       Impact factor: 6.167

Review 3.  Signalling functions and biochemical properties of pertussis toxin-resistant G-proteins.

Authors:  T A Fields; P J Casey
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

4.  GDP stimulates the phosphorylation of a 36-kDa membrane protein in Dictyostelium discoideum.

Authors:  A Anschutz; A Howlet; C Klein
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

5.  Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

Authors:  H Itoh; T Kozasa; S Nagata; S Nakamura; T Katada; M Ui; S Iwai; E Ohtsuka; H Kawasaki; K Suzuki
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

6.  Deduced amino acid sequence of bovine retinal Go alpha: similarities to other guanine nucleotide-binding proteins.

Authors:  K P Van Meurs; C W Angus; S Lavu; H F Kung; S K Czarnecki; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

7.  GTP-binding domain: three consensus sequence elements with distinct spacing.

Authors:  T E Dever; M J Glynias; W C Merrick
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

8.  Identification of the probable site of choleragen-catalyzed ADP-ribosylation in a Go alpha-like protein based on cDNA sequence.

Authors:  C W Angus; K P Van Meurs; S C Tsai; R Adamik; M C Miedel; Y C Pan; H F Kung; J Moss; M Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

9.  Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.

Authors:  T Michel; J W Winslow; J A Smith; J G Seidman; E J Neer
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

10.  Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

Authors:  K A Sullivan; Y C Liao; A Alborzi; B Beiderman; F H Chang; S B Masters; A D Levinson; H R Bourne
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205
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