| Literature DB >> 30815312 |
Ji-Hyun Yun1, Sung-Hwan Park1, Goo-Hee Choi1, In-Jae Park1, Jin-Ha Lee2, Ok-Hwan Lee2, Jung-Hyon Kim3, Yun-Hee Seo4, Ju-Hyun Cho1.
Abstract
The purpose of this study was to determine the antidiabetic effect of an extract of nutricultured Brassica napus containing vanadium (BECV). The BECV was prepared following nutriculture of B. napus with a Jeju water vanadium concentrate for 7 day. The BECV was administered to db/db mice for 8 weeks at different dosages (0.028, 0.14, and 0.7 μg/kg; as vanadium concentration in BECV). After 8 weeks, the BECV results showed mouse blood glucose concentrations to significantly decrease, in a dose-dependent manner, compared with the results for control mice. In addition, the concentrations of triglyceride, total cholesterol, and glycated hemoglobin were significantly lower after 8 weeks of administration of 0.7 μg/kg BECV. Therefore, the BECV may have protective effects against type 2 diabetes.Entities:
Keywords: Antidiabetic effect; Brassica napus extract; Vanadium; db/db mouse
Year: 2018 PMID： 30815312 PMCID： PMC6365333 DOI： 10.1007/s10068-018-0436-8
Source DB: PubMed Journal: Food Sci Biotechnol ISSN： 1226-7708 Impact factor: 2.391