Literature DB >> 3081363

Carbon tetrachloride modulates the rat hepatic microsomal UDP-glucuronyl transferase activity and membrane fluidity.

G Deliconstantinos, M Mykoniatis, D Papadimitriou.   

Abstract

Modulations in rat hepatic microsomal UDP-glucuronyl transferase activity have been observed during carbon tetrachloride (CCl4) poisoning, with a large decrease in the enzyme cooperatively and increase in the membrane fluidity, occurring 30 min after administration. The results strengthen the possibility that an increase in microsomal membrane fluidity may be an early key event in liver injury induced by CCl4.

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Year:  1986        PMID： 3081363     DOI： 10.1007/bf01952457

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  23 in total

1.  Preparation and properties of a phospholipid-free form of microsomal UDP-glucuronyltransferase.

Authors:  R H Erickson; D Zakim; D A Vessey
Journal:  Biochemistry       Date:  1978-09-05       Impact factor: 3.162

2.  Uridine compounds in glucuronic acid metabolism. I. The formation of glucuronides in liver suspensions.

Authors:  G J DUTTON; I D STOREY
Journal:  Biochem J       Date:  1954-06       Impact factor: 3.857

Review 3.  Fluidity parameters of lipid regions determined by fluorescence polarization.

Authors:  M Shinitzky; Y Barenholz
Journal:  Biochim Biophys Acta       Date:  1978-12-15

Review 4.  Carbon tetrachloride hepatotoxicity.

Authors:  R O Recknagel
Journal:  Pharmacol Rev       Date:  1967-06       Impact factor: 25.468

5.  The phospholipid-dependence of uridine diphosphate glucuronyltransferase. Temperature-dependence of microsomal enzyme activity and thermotropic changes in membrane structure.

Authors:  D T Pechey; A B Graham; G C Wood
Journal:  Biochem J       Date:  1978-10-01       Impact factor: 3.857

6.  Lipid structural order parameters (reciprocal of fluidity) in biomembranes derived from steady-state fluorescence polarization measurements.

Authors:  W J Van Blitterswijk; R P Van Hoeven; B W Van der Meer
Journal:  Biochim Biophys Acta       Date:  1981-06-22

7.  Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor.

Authors:  F P Van Roy; K P Heirwegh
Journal:  Biochem J       Date:  1968-04       Impact factor: 3.857

8.  Comparison of different activators and diazotization procedures in the assay of bilirubin-UDP-glucuronyl transferase activity in rat liver.

Authors:  N Tavoloni; M J Jones; R Wittman; C L Kiang; P D Berk
Journal:  Clin Chim Acta       Date:  1983-03-14       Impact factor: 3.786

9.  LIVER PARENCHYMAL CELL INJURY. I. INITIAL ALTERATIONS OF THE CELL FOLLOWING POISONING WITH CARBON TETRACHLORIDE.

Authors:  E S REYNOLDS
Journal:  J Cell Biol       Date:  1963-10       Impact factor: 10.539

10.  Studies on the synthesis and intracellular transport of lipoprotein particles in rat liver.

Authors:  H Glaumann; A Bergstrand; J L Ericsson
Journal:  J Cell Biol       Date:  1975-02       Impact factor: 10.539
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  3 in total

1.  Levels of hepatic stimulator substance in liver regenerating process of partially hepatectomized rats pretreated with a single dose of carbon tetrachloride.

Authors:  A A Liakos; M G Mykoniatis; M E Kokala; D G Papadimitriou; G D Liatsos
Journal:  Dig Dis Sci       Date:  1999-05       Impact factor: 3.199

2.  Abnormal lipid composition of microsomes from cirrhotic rat liver--does it contribute to decreased microsomal function?

Authors:  J Reichen; J T Buters; Z Sojcic; F J Roos
Journal:  Experientia       Date:  1992-05-15

3.  Reversal of carbon tetrachloride induced changes in microviscosity and lipid composition of liver plasma membrane by colchicine in rats.

Authors:  J A Solis-Herruzo; M De Gando; M P Ferrer; I Hernandez Muñoz; B Fernandez-Boya; M P De la Torre; M T Muñoz-Yague
Journal:  Gut       Date:  1993-10       Impact factor: 23.059
  3 in total

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