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Literature DB >> 5660631

Determination of bilirubin glucuronide and assay of glucuronyltransferase with bilirubin as acceptor.

Abstract

1. Conjugated bilirubin is conveniently determined by coupling with the diazonium salt of ethyl anthranilate. 2. This method has been used in the development of assays for UDP-glucuronyltransferase (EC 2.4.1.17), with bilirubin as substrate, in rat liver homogenates, microsomal preparations and partly purified fractions. 3. Chromatographic analysis suggests that bilirubin monoglucuronide is the product of the enzyme systems studied.

Entities: Chemical Species

Mesh：

Substances：

Year: 1968 PMID： 5660631 PMCID： PMC1198694 DOI： 10.1042/bj1070507

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

23 in total

1. BILIRUBIN-PURIFICATION-PURITY.

Authors: J FOG
Journal: Scand J Clin Lab Invest Date: 1964 Impact factor: 1.713

2. COMPARISON OF GLUCURONIDE SYNTHESIS IN DEVELOPING MAMMALIAN AND AVIAN LIVER.

Authors: G J DUTTON
Journal: Ann N Y Acad Sci Date: 1963-12-30 Impact factor: 5.691

3. LIMITATIONS IN THE DETERMINATION OF IN VITRO BILIRUBIN GLUCURONIDE FORMATION.

Authors: R C BOERTH; A H BLATT; J L SPRATT
Journal: J Lab Clin Med Date: 1965-03

4. Studies of conjugated bilirubin. III. Pigment I, a complex of conjugated and free bilirubin.

Authors: C H GREGORY
Journal: J Lab Clin Med Date: 1963-06

5. The synthesis of bilirubin glucuronide by tissue homogenates.

Authors: G M GRODSKY; J V CARBONE
Journal: J Biol Chem Date: 1957-05 Impact factor: 5.157

6. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Authors: C DE DUVE; B C PRESSMAN; R GIANETTO; R WATTIAUX; F APPELMANS
Journal: Biochem J Date: 1955-08 Impact factor: 3.857

7. The preparation and properties of beta-glucuronidase. IV. Inhibition by sugar acids and their lactones.

Authors: G A LEVVY
Journal: Biochem J Date: 1952-11 Impact factor: 3.857

8. Determination of cerebrospinal fluid protein with the Folin phenol reagent.

Authors: W H DAUGHADAY; O H LOWRY; N J ROSEBROUGH; W S FIELDS
Journal: J Lab Clin Med Date: 1952-04

9. Solubilization of N-glucuronyl transferase.

Authors: L L Leventer; J L Buchanan; J E Ross; D F Tapley
Journal: Biochim Biophys Acta Date: 1965-11-22

10. SOME DIFFERENCES IN THE CONJUGATION OF O-AMINOPHENOL AND P-NITROPHENOL BY THE URIDINE DIPHOSPHATE TRANSGLUCURONYLASE OF MOUSE-LIVER HOMOGENATES.

Authors: I D STOREY
Journal: Biochem J Date: 1965-04 Impact factor: 3.857

62 in total

1. A critical amino acid residue, asp446, in UDP-glucuronosyltransferase.

Authors: H Iwano; H Yokota; S Ohgiya; N Yotumoto; A Yuasa
Journal: Biochem J Date: 1997-08-01 Impact factor: 3.857

2. Further studies on the effect of imipramine and desipramine on uridine diphosphate.

Authors: R F Piper; T Hargreaves
Journal: Experientia Date: 1975-02-15

Review 3. New insights into the classification and mechanisms of hereditary, chronic, non-haemolytic hyperbilirubinaemias.

Authors: P Berthelot; D Dhumeaux
Journal: Gut Date: 1978-06 Impact factor: 23.059

4. Heterogeneity of bile pigment conjugates as revealed by chromatography of their ethyl anthranilate azopigments.

Authors: K P Heirwegh; G P Van Hees; P Leroy; F P Van Roy; F H Jansen
Journal: Biochem J Date: 1970-12 Impact factor: 3.857

5. Structures of bilirubin conjugates synthesized in vitro from bilirubin and uridine diphosphate glucuronic acid, uridine diphosphate glucose or uridine diphosphate xylose by preparations from rat liver.

Authors: J Fevery; P Leroy; M Van de Vijver; K P Heirwegh
Journal: Biochem J Date: 1972-09 Impact factor: 3.857

6. Enzymic transfer of glucose and xylose from uridine diphosphate glucose and uridine diphosphate xylose to bilirubin by untreated and digitonin-activated preparations from rat liver.

Authors: J Fevery; P Leroy; K P Heirwegh
Journal: Biochem J Date: 1972-09 Impact factor: 3.857

7. Assay and properties of dititonin-activated bilirubin uridine diphosphate glucuronyltransferase from rat liver.

Authors: K P Heirwegh; M Van de Vijver; J Fevery
Journal: Biochem J Date: 1972-09 Impact factor: 3.857

8. The effect of steroids and nucleotidesoon solubilized bilirubin uridine diphosphate-glucuronyltransferase.

Authors: B P Adlard; G H Lathe
Journal: Biochem J Date: 1970-09 Impact factor: 3.857

9. Estimation of hepatic bilirubin UDP-glucuronyl transferase in patients with noncirrhotic portal fibrosis and liver disease: Significance and limitations.

Authors: D V Datta; R Nair; C R Nair
Journal: Am J Dig Dis Date: 1975-10

10. The isolation of an azobilirubin beta-D-monoglucoside from dog gall-bladder bile.

Authors: E R Gordon; M Dadoun; C A Goresky; T H Chan; A S Perlin
Journal: Biochem J Date: 1974-10 Impact factor: 3.857