Literature DB >> 3080009

Uptake of alpha-difluoromethylornithine by Trypanosoma brucei brucei.

A J Bitonti, C J Bacchi, P P McCann, A Sjoerdsma.   

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Year:  1986        PMID： 3080009     DOI： 10.1016/0006-2952(86)90539-3

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  9 in total

1.  Alterations in ornithine decarboxylase characteristics account for tolerance of Trypanosoma brucei rhodesiense to D,L-alpha-difluoromethylornithine.

Authors:  M Iten; H Mett; A Evans; J C Enyaru; R Brun; R Kaminsky
Journal:  Antimicrob Agents Chemother       Date:  1997-09       Impact factor: 5.191

Review 2.  Eflornithine. A new drug in the treatment of sleeping sickness.

Authors:  I Van Bogaert; A Haemers
Journal:  Pharm Weekbl Sci       Date:  1989-06-23

3.  A molecular mechanism for eflornithine resistance in African trypanosomes.

Authors:  Isabel M Vincent; Darren Creek; David G Watson; Mohammed A Kamleh; Debra J Woods; Pui Ee Wong; Richard J S Burchmore; Michael P Barrett
Journal:  PLoS Pathog       Date:  2010-11-24       Impact factor: 6.823

4.  Regulation of polyamine biosynthesis in rat hepatoma (HTC) cells by a bisbenzyl polyamine analogue.

Authors:  A J Bitonti; T L Bush; P P McCann
Journal:  Biochem J       Date:  1989-02-01       Impact factor: 3.857

5.  DL-alpha-difluoromethyl[3,4-3H]arginine metabolism in tobacco and mammalian cells. Inhibition of ornithine decarboxylase activity after arginase-mediated hydrolysis of DL-alpha-difluoromethylarginine to DL-alpha-difluoromethylornithine.

Authors:  R D Slocum; A J Bitonti; P P McCann; R P Feirer
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

Review 6.  Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.

Authors:  M P Barrett; D W Boykin; R Brun; R R Tidwell
Journal:  Br J Pharmacol       Date:  2007-07-09       Impact factor: 8.739

7.  The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain.

Authors:  Lisa Sanderson; Murat Dogruel; Jean Rodgers; Barbara Bradley; Sarah Ann Thomas
Journal:  J Neurochem       Date:  2008-09-24       Impact factor: 5.372

8.  Chemotherapy of human african trypanosomiasis.

Authors:  Cyrus J Bacchi
Journal:  Interdiscip Perspect Infect Dis       Date:  2009-08-20

Review 9.  The Drugs of Sleeping Sickness: Their Mechanisms of Action and Resistance, and a Brief History.

Authors:  Harry P De Koning
Journal:  Trop Med Infect Dis       Date:  2020-01-19
  9 in total

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