| Literature DB >> 30797228 |
Ilana N Ackerman1,2, Megan A Bohensky3, Ella Zomer4, Mark Tacey4,5,6, Alexandra Gorelik3,7, Caroline A Brand4, Richard de Steiger8,9.
Abstract
BACKGROUND: Comprehensive national joint replacement registries with well-validated data offer unique opportunities for examining the potential future burden of hip and knee osteoarthritis (OA) at a population level. This study aimed to forecast the burden of primary total knee (TKR) and hip replacements (THR) performed for OA in Australia to the year 2030, and to model the impact of contrasting obesity scenarios on TKR burden.Entities:
Keywords: Economic burden of disease; Obesity; Osteoarthritis; Total hip replacement; Total knee replacement
Mesh:
Year: 2019 PMID: 30797228 PMCID: PMC6387488 DOI: 10.1186/s12891-019-2411-9
Source DB: PubMed Journal: BMC Musculoskelet Disord ISSN: 1471-2474 Impact factor: 2.362
Joint replacement demographics and estimated costs in 2003 and 2013
| Total knee replacement | Total hip replacement | |||
|---|---|---|---|---|
| 2003 | 2013 | 2003 | 2013 | |
| Procedures | ||||
| Total, | 20,986 | 42,920 | 15,031 | 25,945 |
| Females, | 12,004 (57.2) | 24,305 (56.6) | 8192 (54.5) | 13,830 (53.3) |
| Aged ≥70 years, | 11,206 (53.4) | 19,115 (44.5) | 7701 (51.2) | 11,655 (44.9) |
| Private hospital, | 13,650 (65.0) | 29,783 (69.4) | 9581 (64.1) | 18,163 (70.0) |
| Metropolitan hospital, | 13,687 (65.2) | 27,557 (64.6) | 10,107 (67.2) | 17,556 (67.7) |
| > 1 procedure in same yeara, | 2824 (13.5) | 6978 (16.3) | 860 (5.7) | 1688 (6.5) |
| Estimated costsb | ||||
| Overall health system | $448 million | $905 million | $364 million | $625 million |
| Private health system only | $272 million | $591 million | $227 million | $429 million |
| Public health system only | $176 million | $314 million | $137 million | $196 million |
aTwo or more procedures in the same year and same hospital setting were classified as bilateral simultaneous procedures for costing purposes
bAll costs are reported in 2016 Australian dollars
Fig. 1Growth in number of total knee replacements from 2003 to 2030 under Scenario 1. Number of total knee replacement procedures for 2003–2013 is based on numbers reported to the AOANJRR. Number of procedures from 2014 onwards is based on projections under Scenario 1
Fig. 2Growth in number of total hip replacements from 2003 to 2030 under Scenario 1. Number of total hip replacement procedures for 2003–2013 is based on numbers reported to the AOANJRR. Number of procedures from 2014 onwards is based on projections under Scenario 1
Fig. 3Growth in number of total knee replacements from 2003 to 2030 under Scenario 2. Number of total knee replacement procedures for 2003–2013 is based on numbers reported to the AOANJRR. Number of procedures from 2014 onwards is based on projections under Scenario 2
Fig. 4Growth in number of total hip replacements from 2003 to 2030 under Scenario 2. Number of total hip replacement procedures for 2003–2013 is based on numbers reported to the AOANJRR. Number of procedures from 2014 onwards is based on projections under Scenario 2
Total knee replacement projections and costs in 2030 with changes in obesity rates
| Projected burden | Change in burden based on changes in obesity rates | |||
|---|---|---|---|---|
| Projection scenario | Procedures ( | Cost | Procedures ( | Cost |
| Scenario 1 (constant TKR rate) | ||||
| Base projection | 65,569 | $1.38 billion | ||
| Sensitivity analysis - increasing overweight/obesity | 75,602 | $1.59 billion | + 10,033 | +$212 million |
| Sensitivity analysis - decreasing overweight/obesity | ||||
| 1% | 64,913 | $1.37 billion | −656 | -$14 million |
| 2% | 64,257 | $1.35 billion | − 1312 | -$28 million |
| 3% | 63,602 | $1.34 billion | − 1967 | -$41 million |
| 4% | 62,946 | $1.33 billion | − 2623 | -$55 million |
| 5% | 62,290 | $1.31 billion | − 3279 | -$69 million |
| Scenario 2 (increasing TKR rate) | ||||
| Base projection | 161,231 | $3.40 billion | ||
| Sensitivity analysis - increasing overweight/obesity | 185,938 | $3.92 billion | + 24,707 | +$521 million |
| Sensitivity analysis - decreasing overweight/obesity | ||||
| 1% | 159,619 | $3.37 billion | −1612 | -$34 million |
| 2% | 158,006 | $3.33 billion | − 3225 | -$68 million |
| 3% | 156,394 | $3.30 billion | − 4837 | -$102 million |
| 4% | 154,782 | $3.26 billion | − 6449 | -$136 million |
| 5% | 153,169 | $3.23 billion | −8062 | -$170 million |
All costs are reported in 2016 Australian dollars