Daniel R Kramer1,2, Michael F Barbaro3, Morgan Lee3, Terrance Peng3, George Nune4,5, Charles Y Liu3,6,7,5, Spencer Kellis3,6,7,5, Brian Lee3,5. 1. Department of Neurosurgery, University of Southern California, 1200 N. State Street, Suite 3300, Los Angeles, CA, 90033, USA. drk_431@usc.edu. 2. Neurorestoration Center, University of Southern California, Los Angeles, CA, USA. drk_431@usc.edu. 3. Department of Neurosurgery, University of Southern California, 1200 N. State Street, Suite 3300, Los Angeles, CA, 90033, USA. 4. Department of Neurology, University of Southern California, Los Angeles, CA, USA. 5. Neurorestoration Center, University of Southern California, Los Angeles, CA, USA. 6. Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. 7. Tianqiao and Chrissy Chen Brain-machine Interface Center, California Institute of Technology, Pasadena, CA, USA.
Abstract
OBJECTIVE: Restoration of somatosensory deficits in humans requires a clear understanding of the neural representations of percepts. To characterize the cortical response to naturalistic somatosensation, we examined field potentials in the primary somatosensory cortex of humans. METHODS: Four patients with intractable epilepsy were implanted with subdural electrocorticography (ECoG) electrodes over the hand area of S1. Three types of stimuli were applied, soft-repetitive touch, light touch, and deep touch. Power in the alpha (8-15 Hz), beta (15-30 Hz), low-gamma (30-50 Hz), and high-gamma (50-125 Hz) frequency bands were evaluated for significance. RESULTS: Seventy-seven percent of electrodes over the hand area of somatosensory cortex exhibited changes in these bands. High-gamma band power increased for all stimuli, with concurrent alpha and beta band power decreases. Earlier activity was seen in these bands in deep touch and light touch compared to soft touch. CONCLUSIONS: These findings are consistent with prior literature and suggest a widespread response to focal touch, and a different encoding of deeper pressure touch than soft touch.
OBJECTIVE: Restoration of somatosensory deficits in humans requires a clear understanding of the neural representations of percepts. To characterize the cortical response to naturalistic somatosensation, we examined field potentials in the primary somatosensory cortex of humans. METHODS: Four patients with intractable epilepsy were implanted with subdural electrocorticography (ECoG) electrodes over the hand area of S1. Three types of stimuli were applied, soft-repetitive touch, light touch, and deep touch. Power in the alpha (8-15 Hz), beta (15-30 Hz), low-gamma (30-50 Hz), and high-gamma (50-125 Hz) frequency bands were evaluated for significance. RESULTS: Seventy-seven percent of electrodes over the hand area of somatosensory cortex exhibited changes in these bands. High-gamma band power increased for all stimuli, with concurrent alpha and beta band power decreases. Earlier activity was seen in these bands in deep touch and light touch compared to soft touch. CONCLUSIONS: These findings are consistent with prior literature and suggest a widespread response to focal touch, and a different encoding of deeper pressure touch than soft touch.
Authors: Stefan Debener; Christoph S Herrmann; Cornelia Kranczioch; Daniel Gembris; Andreas K Engel Journal: Neuroreport Date: 2003-04-15 Impact factor: 1.837
Authors: Daniel R Kramer; Krista Lamorie-Foote; Michael Barbaro; Morgan B Lee; Terrance Peng; Angad Gogia; George Nune; Charles Y Liu; Spencer S Kellis; Brian Lee Journal: Neurosurg Focus Date: 2020-02-01 Impact factor: 4.047