Literature DB >> 30784002

New otonecine-type pyrrolizidine alkaloid from Petasites japonicus.

Mariko Kitajima1, Kei Okabe1, Megumi Yoshida1, Ryo Nakabayashi2, Kazuki Saito1,2, Noriyuki Kogure1, Hiromitsu Takayama3.   

Abstract

One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine (3), and senkirkine (4), was isolated from the whole plant of Petasites japonicus. The structure of 1 was determined by spectroscopic analyses and chemical conversion from the known alkaloid petasitenine (2).

Entities:  

Keywords:  HPLC analysis; Otonecine; Petasitenine; Petasites japonicus; Pyrrolizidine alkaloid

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Substances：

Year:  2019        PMID： 30784002     DOI： 10.1007/s11418-019-01285-9

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  8 in total

1.  Fukinotoxin, a new pyrrolizidine alkaloid from Petasites japonicus.

Authors:  T Furuya; M Hikichi; Y Iitaka
Journal:  Chem Pharm Bull (Tokyo)       Date:  1976-05       Impact factor: 1.645

2.  Separation and determination of macrocyclic pyrrolizidine alkaloids of the otonecine type present in the edible plant Petasites japonicus by reversed-phase high-performance liquid chromatography.

Authors:  H Niwa; H Ishiwata; K Yamada
Journal:  J Chromatogr       Date:  1983-02-25

3.  Asymmetric Total Synthesis of Pentacyclic Indole Alkaloid Andranginine and Absolute Configuration of Natural Product Isolated from Kopsia arborea.

Authors:  Shino Tooriyama; Yuji Mimori; Yuqiu Wu; Noriyuki Kogure; Mariko Kitajima; Hiromitsu Takayama
Journal:  Org Lett       Date:  2017-05-08       Impact factor: 6.005

4.  Pyrrolizidine Alkaloid-Protein Adducts: Potential Non-invasive Biomarkers of Pyrrolizidine Alkaloid-Induced Liver Toxicity and Exposure.

Authors:  Qingsu Xia; Yuewei Zhao; Ge Lin; Frederick A Beland; Lining Cai; Peter P Fu
Journal:  Chem Res Toxicol       Date:  2016-07-21       Impact factor: 3.739

5.  A Cyclopeptide and a Tetrahydroisoquinoline Alkaloid from Ophiorrhiza nutans.

Authors:  Tadayoshi Onozawa; Mariko Kitajima; Noriyuki Kogure; Nichakan Peerakam; Dammrong Santiarworn; Hiromitsu Takayama
Journal:  J Nat Prod       Date:  2017-07-20       Impact factor: 4.050

6.  Determination of hepatotoxic pyrrolizidine alkaloids by on-line high performance liquid chromatography mass spectrometry with an electrospray interface.

Authors:  G Lin; K Y Zhou; X G Zhao; Z T Wang; P P But
Journal:  Rapid Commun Mass Spectrom       Date:  1998       Impact factor: 2.419

Review 7.  Pyrrolizidine alkaloids--genotoxicity, metabolism enzymes, metabolic activation, and mechanisms.

Authors:  Peter P Fu; Qingsu Xia; Ge Lin; Ming W Chou
Journal:  Drug Metab Rev       Date:  2004-02       Impact factor: 4.518

8.  Evaluation of certain food additives and contaminants. Eightieth report of the Joint FAO/WHO Expert Committee on Food Additives.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  2016
  8 in total

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