Choonghee Park1, Moonyoung Hwang1, Yongwook Baek1, Soonwon Jung1, Youngmee Lee1, Domyung Paek2, Kyungho Choi3. 1. Environmental Health Research Division, National Institute of Environmental Research, Ministry of Environment, Incheon, South Korea. 2. Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea. 3. Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea. Electronic address: kyungho@snu.ac.kr.
Abstract
BACKDGROUND: Phthalates and bisphenol A (BPA) have been used in a variety of consumer products and are detected widely in both humans and the environment. Demographic and socio-economic characteristics that affect exposure to these chemicals have been investigated among several general populations; however, nationally-representative population-based studies are limited to Canada, Germany, and the USA. Moreover, relatively little is known about the socio-demographic characteristics that influence exposure to these chemicals among nationally representative populations of Asia. METHODS: Data are obtained from the Korean National Environmental Health Survey (2012-2014). In total, 6,478 adults (aged 19 and older) were recruited and sampled for urinary levels of major phthalate metabolites and bisphenol A. In addition, demographic and socio-economic parameters were determined from questionnaire data and the characteristics associated with urinary concentrations of the target chemicals were assessed. RESULTS: Urinary levels of bis(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) metabolites of Korean adults were generally higher, but those of mono-benzyl phthalate (MBzP) were lower, and BPA were similar or higher than those reported from national biomonitoring programs in the United States and Canada. Similar to other nationally representative populations, females and older adults showed higher creatinine-adjusted phthalate metabolite and BPA levels among the Korean population. Meanwhile, monthly household income and education were negatively associated with urinary phthalate metabolites. Among personal care products, nail polish use was positively associated with both phthalate metabolites and BPA concentrations in urine. CONCLUSION: Our observations based on a nationally representative population of Korea show that socio-demographic determinants for these urinary chemicals vary by country, and should be considered for developing appropriate mitigation measures and policies.
BACKDGROUND: Phthalates and bisphenol A (BPA) have been used in a variety of consumer products and are detected widely in both humans and the environment. Demographic and socio-economic characteristics that affect exposure to these chemicals have been investigated among several general populations; however, nationally-representative population-based studies are limited to Canada, Germany, and the USA. Moreover, relatively little is known about the socio-demographic characteristics that influence exposure to these chemicals among nationally representative populations of Asia. METHODS: Data are obtained from the Korean National Environmental Health Survey (2012-2014). In total, 6,478 adults (aged 19 and older) were recruited and sampled for urinary levels of major phthalate metabolites and bisphenol A. In addition, demographic and socio-economic parameters were determined from questionnaire data and the characteristics associated with urinary concentrations of the target chemicals were assessed. RESULTS: Urinary levels of bis(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP) metabolites of Korean adults were generally higher, but those of mono-benzyl phthalate (MBzP) were lower, and BPA were similar or higher than those reported from national biomonitoring programs in the United States and Canada. Similar to other nationally representative populations, females and older adults showed higher creatinine-adjusted phthalate metabolite and BPA levels among the Korean population. Meanwhile, monthly household income and education were negatively associated with urinary phthalate metabolites. Among personal care products, nail polish use was positively associated with both phthalate metabolites and BPA concentrations in urine. CONCLUSION: Our observations based on a nationally representative population of Korea show that socio-demographic determinants for these urinary chemicals vary by country, and should be considered for developing appropriate mitigation measures and policies.
Authors: Elena Domínguez-Romero; Klára Komprdová; Jiří Kalina; Jos Bessems; Spyros Karakitsios; Dimosthenis A Sarigiannis; Martin Scheringer Journal: J Expo Sci Environ Epidemiol Date: 2022-05-05 Impact factor: 5.563
Authors: Manori J Silva; Lee-Yang Wong; James L Preau; Ella Samandar; Emmanuela Obi; Antonia M Calafat; Julianne C Botelho Journal: Toxics Date: 2019-10-11