Literature DB >> 30772463

Secoiridoids of olive and derivatives as potential coadjuvant drugs in cancer: A critical analysis of experimental studies.

Marilena Celano1, Valentina Maggisano1, Saverio Massimo Lepore1, Diego Russo1, Stefania Bulotta2.   

Abstract

Phenolic secoiridoids from olive, including oleocanthal, oleuropein and related derivatives, are bioactive natural products with documented anticancer activities, that have mainly been attributed to their antioxidant, anti-inflammatory and antiproliferative effects. This review summarizes the results of the preclinical studies on the natural secoiridoids of olive used as single agents or in combination with other chemotherapeutics against cancer cells. The molecular targets of their action are described. A critical analysis of the importance of the experimental studies in view of the possible use in humans is also discussed.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Adjuvant; Cancer; Hydroxytyrosol; Hydroxytyrosol (CID: 82755); Oleacein (CID: 18684078); Oleocanthal; Oleocanthal (CID: 11652416); Oleuropein; Oleuropein (CID: 5281544); Oleuropein aglycone (CID: 56842347); Olive secoiridoids; Tyrosol (CID: 10393)

Mesh：

Substances：

Year:  2019        PMID： 30772463     DOI： 10.1016/j.phrs.2019.01.045

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN： 1043-6618            Impact factor:   7.658


  10 in total

Review 1.  Phytochemicals in thyroid cancer: analysis of the preclinical studies.

Authors:  Stefania Bulotta; Francesca Capriglione; Marilena Celano; Valeria Pecce; Diego Russo; Valentina Maggisano
Journal:  Endocrine       Date:  2021-02-15       Impact factor: 3.633

2.  Quercetin improves the effects of sorafenib on growth and migration of thyroid cancer cells.

Authors:  Marilena Celano; Valentina Maggisano; Stefania Bulotta; Lorenzo Allegri; Valeria Pecce; Luana Abballe; Giuseppe Damante; Diego Russo
Journal:  Endocrine       Date:  2019-11-27       Impact factor: 3.633

3.  Oleacein Prevents High Fat Diet-Induced Adiposity and Ameliorates Some Biochemical Parameters of Insulin Sensitivity in Mice.

Authors:  Saverio Massimo Lepore; Valentina Maggisano; Stefania Bulotta; Chiara Mignogna; Biagio Arcidiacono; Antonio Procopio; Antonio Brunetti; Diego Russo; Marilena Celano
Journal:  Nutrients       Date:  2019-08-07       Impact factor: 5.717

4.  Management of Plant Physiology with Beneficial Bacteria to Improve Leaf Bioactive Profiles and Plant Adaptation under Saline Stress in Olea europea L.

Authors:  Estrella Galicia-Campos; Beatriz Ramos-Solano; Mª Belén Montero-Palmero; F Javier Gutierrez-Mañero; Ana García-Villaraco
Journal:  Foods       Date:  2020-01-07

5.  Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity.

Authors:  Elisabet Cuyàs; Juan Gumuzio; Jesús Lozano-Sánchez; Antonio Segura-Carretero; Sara Verdura; Joaquim Bosch-Barrera; Begoña Martin-Castillo; Alfons Nonell-Canals; Amadeu Llebaria; Silvia Cabello; Carme Serra; Melchor Sanchez-Martinez; Ángel G Martin; Javier A Menendez
Journal:  Aging (Albany NY)       Date:  2020-11-09       Impact factor: 5.682

6.  Molecular Docking and Molecular Dynamics Aided Virtual Search of OliveNet™ Directory for Secoiridoids to Combat SARS-CoV-2 Infection and Associated Hyperinflammatory Responses.

Authors:  Neelaveni Thangavel; Mohammad Al Bratty; Hassan Ahmad Al Hazmi; Asim Najmi; Reem Othman Ali Alaqi
Journal:  Front Mol Biosci       Date:  2021-01-07

Review 7.  A Review of the Effects of Olive Oil-Cooking on Phenolic Compounds.

Authors:  Roberto Ambra; Sabrina Lucchetti; Gianni Pastore
Journal:  Molecules       Date:  2022-01-20       Impact factor: 4.411

Review 8.  Nutraceuticals and Cancer: Potential for Natural Polyphenols.

Authors:  Jessica Maiuolo; Micaela Gliozzi; Cristina Carresi; Vincenzo Musolino; Francesca Oppedisano; Federica Scarano; Saverio Nucera; Miriam Scicchitano; Francesca Bosco; Roberta Macri; Stefano Ruga; Antonio Cardamone; Annarita Coppoletta; Annachiara Mollace; Francesco Cognetti; Vincenzo Mollace
Journal:  Nutrients       Date:  2021-10-27       Impact factor: 6.706

9.  Bacillus H47 triggers Olea europaea metabolism activating DOXP and shikimate pathways simultaneously and modifying leaf extracts' antihypertensive activity.

Authors:  Estrella Galicia-Campos; Ana García-Villaraco; M B Montero-Palmero; F Javier Gutiérrez-Mañero; Beatriz Ramos-Solano
Journal:  Front Microbiol       Date:  2022-10-04       Impact factor: 6.064

10.  Multifloroside Suppressing Proliferation and Colony Formation, Inducing S Cell Cycle Arrest, ROS Production, and Increasing MMP in Human Epidermoid Carcinoma Cell Lines A431.

Authors:  Xin Zhang; Yamei Li; Zhengping Feng; Yaling Zhang; Ye Gong; Huanhuan Song; Xiaoli Ding; Yaping Yan
Journal:  Molecules       Date:  2019-12-18       Impact factor: 4.411
  10 in total

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