Literature DB >> 30771392

Chitosan nanopolymers: An overview of drug delivery against cancer.

Rajasree Shanmuganathan1, Thomas Nesakumar Jebakumar Immanuel Edison2, Felix LewisOscar3, Ponnuchamy Kumar4, Sabarathinam Shanmugam5, Arivalagan Pugazhendhi6.   

Abstract

Cancer is becoming a major reason for death troll worldwide due to the difficulty in finding an efficient, cost effective and target specific method of treatment or diagnosis. The variety of cancer therapy used in the present scenario have painful side effects, low effectiveness and high cost, which are some major drawbacks of the available therapies. Apart from the conventional cancer therapy, nanotechnology has grown extremely towards treating cancer. Nanotechnology is a promising area of science focusing on developing target specific drug delivery system for carrying small or large active molecules to diagnose and treat cancer cells. In the field of nanoscience, Chitosan nanopolymers (ChNPs) are been emerging as a potential carrier due to their biodegradability and biocompatibility. The easy modification and versatility in administration route of ChNPs has attracted attention of researchers towards loading chemicals, proteins and gene drugs for target specific therapy of cancer cells. Therefore, the present review deals with the growing concern towards cancer therapy, introduction of ChNPs, mode of action and other strategies employed by researchers till date towards cancer treatment and diagnosis ChNPs.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer therapy; Chitosan; Nanotechnology

Mesh:

Substances:

Year:  2019        PMID: 30771392     DOI: 10.1016/j.ijbiomac.2019.02.060

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  28 in total

1.  Hydroxyurea-loaded Fe3O4/SiO2/chitosan-g-mPEG2000 nanoparticles; pH-dependent drug release and evaluation of cell cycle arrest and altering p53 and lincRNA-p21 genes expression.

Authors:  Mahsa Moeini Chaghervand; Maryam Bikhof Torbati; Masoud Shaabanzadeh; Adeleh Ahmadi; Farzaneh Tafvizi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2021-10-18       Impact factor: 3.000

2.  Chitosan And N, N, N-Trimethyl Chitosan Nanoparticle Encapsulation Of Ocimum Gratissimum Essential Oil: Optimised Synthesis, In Vitro Release And Bioactivity.

Authors:  Confidence Onyebuchi; Doğa Kavaz
Journal:  Int J Nanomedicine       Date:  2019-09-20

3.  Graphene-based hybrid nanoparticle of doxorubicin for cancer chemotherapy.

Authors:  Nagaraja SreeHarsha; Rahul Maheshwari; Bandar E Al-Dhubiab; Muktika Tekade; Mukesh Chandra Sharma; Katharigatta N Venugopala; Rakesh Kumar Tekade; Abdullah M Alzahrani
Journal:  Int J Nanomedicine       Date:  2019-09-12

4.  Stimulus Responsive Ocular Gentamycin-Ferrying Chitosan Nanoparticles Hydrogel: Formulation Optimization, Ocular Safety and Antibacterial Assessment.

Authors:  Nabil K Alruwaili; Ameeduzzafar Zafar; Syed Sarim Imam; Khalid Saad Alharbi; Nasser Hadal Alotaibi; Sultan Alshehri; Nabil A Alhakamy; Abdulaziz I Alzarea; Muhammad Afzal; Mohammed Elmowafy
Journal:  Int J Nanomedicine       Date:  2020-06-30

5.  Thiolated polymer nanocarrier reinforced with glycyrrhetinic acid for targeted delivery of 5-fluorouracil in hepatocellular carcinoma.

Authors:  Sachin S Bhat; Dhrubojyoti Mukherjee; Pinal Sukharamwala; Rachita Dehuri; Anita Murali; Banala Venkatesh Teja
Journal:  Drug Deliv Transl Res       Date:  2021-01-11       Impact factor: 4.617

Review 6.  A review of the tortuous path of nonviral gene delivery and recent progress.

Authors:  Divya Sharma; Sanjay Arora; Jagdish Singh; Buddhadev Layek
Journal:  Int J Biol Macromol       Date:  2021-06-01       Impact factor: 8.025

7.  Biosynthesis of chitosan-coated iron oxide (Fe3O4) hybrid nanocomposites from leaf extracts of Brassica oleracea L. and study on their antibacterial potentials.

Authors:  Manikandan Appu; Zhifeng Lian; Dengqi Zhao; Jianying Huang
Journal:  3 Biotech       Date:  2021-05-16       Impact factor: 2.893

8.  A novel bacterial β-N-acetyl glucosaminidase from Chitinolyticbacter meiyuanensis possessing transglycosylation and reverse hydrolysis activities.

Authors:  Alei Zhang; Xiaofang Mo; Ning Zhou; Yingying Wang; Guoguang Wei; Jie Chen; Kequan Chen; Pingkai Ouyang
Journal:  Biotechnol Biofuels       Date:  2020-06-29       Impact factor: 6.040

Review 9.  Chitosan Nanoparticles for Therapy and Theranostics of Hepatocellular Carcinoma (HCC) and Liver-Targeting.

Authors:  Maria Cristina Bonferoni; Elisabetta Gavini; Giovanna Rassu; Marcello Maestri; Paolo Giunchedi
Journal:  Nanomaterials (Basel)       Date:  2020-04-30       Impact factor: 5.076

Review 10.  Chitosan-Based Nanoparticles of Targeted Drug Delivery System in Breast Cancer Treatment.

Authors:  Yedi Herdiana; Nasrul Wathoni; Shaharum Shamsuddin; I Made Joni; Muchtaridi Muchtaridi
Journal:  Polymers (Basel)       Date:  2021-05-24       Impact factor: 4.329

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