Orkide Kutlu1, Selma Şengiz Erhan2, Yasemin Gökden3, Özlem Kandemir3, Tufan Tükek4. 1. Department of Internal Medicine, Okmeydanı Education and Research Hospital, Istanbul, Turkey, orkidekutlu@windowslive.com. 2. Department of Pathology, Okmeydanı Education and Research Hospital, Istanbul, Turkey. 3. Department of Internal Medicine, Okmeydanı Education and Research Hospital, Istanbul, Turkey. 4. Istanbul University Faculty of Medicine, Istanbul, Turkey.
Abstract
OBJECTIVE: Whipple's disease is a very rare systemic infectious disease with an annual incidence of 3 in one million, which may be fatal if not diagnosed and treated appropriately. CLINICAL PRESENTATION AND INTERVENTION: Herein we describe a 49-year-old patient admitted to the hospital with symptoms of severe malabsorption and diagnosed with Whipple's disease. The diagnosis was based on the histopathological findings of small intestine biopsies and PCR analysis. CONCLUSION: Whipple's disease should be kept in mind while dealing with patients with severe malabsorption, even in the absence of accompanying features of the disease.
OBJECTIVE:Whipple's disease is a very rare systemic infectious disease with an annual incidence of 3 in one million, which may be fatal if not diagnosed and treated appropriately. CLINICAL PRESENTATION AND INTERVENTION: Herein we describe a 49-year-old patient admitted to the hospital with symptoms of severe malabsorption and diagnosed with Whipple's disease. The diagnosis was based on the histopathological findings of small intestine biopsies and PCR analysis. CONCLUSION:Whipple's disease should be kept in mind while dealing with patients with severe malabsorption, even in the absence of accompanying features of the disease.
Authors: F Biagi; D Balduzzi; P Delvino; A Schiepatti; C Klersy; G R Corazza Journal: Eur J Clin Microbiol Infect Dis Date: 2015-03-25 Impact factor: 3.267