| Literature DB >> 30756310 |
Sri Murugan Poongkavithai Vadevoo1,2, Smriti Gurung1,2, Fatima Khan1,2, Md Enamul Haque1,2, Gowri Rangaswamy Gunassekaran1,2, Lianhua Chi1,2, Uttapol Permpoon1,2, Byungheon Lee3,4.
Abstract
Peptides have advantages over antibodies in terms of deep tissue penetration, low immunogenicity, and cost-effective production, but they have short circulation time and poor stability in vivo. Peptides have been extensively used as targeting moieties for the delivery of drug-loaded nanoparticles and function as targeted therapeutics in cancer treatment. Here, we review peptides that are exploited as targeted therapeutics in cancer therapy and apoptosis imaging probes for the monitoring of treatment responses.Entities:
Keywords: Apoptosis; CD44v6; Imaging; PD-L1; Phage display; Pro-apoptotic peptide; Targeted therapeutics
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Year: 2019 PMID： 30756310 DOI： 10.1007/s12272-019-01125-0
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946