Literature DB >> 30755707

Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation.

Meng-Meng Zhang1, Na Liu2, Yuan-Liang Zhang1, Bowen Rong3, Xiao-Lin Wang1, Chun-Hui Xu2, Yin-Yin Xie1, Shuhong Shen4, Jiang Zhu1, Stephen D Nimer5, Zhu Chen1, Sai-Juan Chen1, Robert G Roeder6, Fei Lan3, Lan Wang7, Qiu-Hua Huang8, Xiao-Jian Sun9.   

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Year:  2019        PMID： 30755707      PMCID： PMC6880927          DOI： 10.1038/s41375-019-0398-8

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  16 in total

Review 1.  Transcription factors in myeloid development: balancing differentiation with transformation.

Authors:  Frank Rosenbauer; Daniel G Tenen
Journal:  Nat Rev Immunol       Date:  2007-02       Impact factor: 53.106

2.  Transient depletion of RUNX1/RUNX1T1 by RNA interference delays tumour formation in vivo.

Authors:  N Martinez Soria; R Tussiwand; P Ziegler; M G Manz; O Heidenreich
Journal:  Leukemia       Date:  2008-06-12       Impact factor: 11.528

3.  Intrinsic protein disorder and interaction promiscuity are widely associated with dosage sensitivity.

Authors:  Tanya Vavouri; Jennifer I Semple; Rosa Garcia-Verdugo; Ben Lehner
Journal:  Cell       Date:  2009-07-10       Impact factor: 41.582

4.  Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.

Authors:  Michael Bots; Inge Verbrugge; Benjamin P Martin; Jessica M Salmon; Margherita Ghisi; Adele Baker; Kym Stanley; Jake Shortt; Gert J Ossenkoppele; Johannes Zuber; Amy R Rappaport; Peter Atadja; Scott W Lowe; Ricky W Johnstone
Journal:  Blood       Date:  2014-01-10       Impact factor: 22.113

5.  Disorder, promiscuity, and toxic partnerships.

Authors:  Edward M Marcotte; Mark Tsechansky
Journal:  Cell       Date:  2009-07-10       Impact factor: 41.582

6.  Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Authors:  A Ptasinska; S A Assi; D Mannari; S R James; D Williamson; J Dunne; M Hoogenkamp; M Wu; M Care; H McNeill; P Cauchy; M Cullen; R M Tooze; D G Tenen; B D Young; P N Cockerill; D R Westhead; O Heidenreich; C Bonifer
Journal:  Leukemia       Date:  2012-02-20       Impact factor: 11.528

7.  Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model.

Authors:  Nina Cabezas-Wallscheid; Victoria Eichwald; Jos de Graaf; Martin Löwer; Hans-Anton Lehr; Andreas Kreft; Leonid Eshkind; Andreas Hildebrandt; Yasmin Abassi; Rosario Heck; Anna Katharina Dehof; Svetlana Ohngemach; Rolf Sprengel; Simone Wörtge; Steffen Schmitt; Johannes Lotz; Claudius Meyer; Thomas Kindler; Dong-Er Zhang; Bernd Kaina; John C Castle; Andreas Trumpp; Ugur Sahin; Ernesto Bockamp
Journal:  EMBO Mol Med       Date:  2013-10-04       Impact factor: 12.137

8.  A simple principle concerning the robustness of protein complex activity to changes in gene expression.

Authors:  Jennifer I Semple; Tanya Vavouri; Ben Lehner
Journal:  BMC Syst Biol       Date:  2008-01-02

9.  A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

Authors:  Xiao-Jian Sun; Zhanxin Wang; Lan Wang; Yanwen Jiang; Nils Kost; T David Soong; Wei-Yi Chen; Zhanyun Tang; Tomoyoshi Nakadai; Olivier Elemento; Wolfgang Fischle; Ari Melnick; Dinshaw J Patel; Stephen D Nimer; Robert G Roeder
Journal:  Nature       Date:  2013-06-30       Impact factor: 49.962

10.  Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Authors:  Anetta Ptasinska; Salam A Assi; Natalia Martinez-Soria; Maria Rosaria Imperato; Jason Piper; Pierre Cauchy; Anna Pickin; Sally R James; Maarten Hoogenkamp; Dan Williamson; Mengchu Wu; Daniel G Tenen; Sascha Ott; David R Westhead; Peter N Cockerill; Olaf Heidenreich; Constanze Bonifer
Journal:  Cell Rep       Date:  2014-09-18       Impact factor: 9.423
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  2 in total

1.  LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.

Authors:  Qian Chen; Murat A Cevher; Qi Jiang; Saisai Wang; Xiaojian Sun; Robert G Roeder; Mo Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2022-10-10       Impact factor: 12.779

2.  A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation.

Authors:  Yi-Fan Zhang; Xiao-Lin Wang; Chun-Hui Xu; Na Liu; Ling Zhang; Yu-Ming Zhang; Yin-Yin Xie; Yuan-Liang Zhang; Qiu-Hua Huang; Lan Wang; Zhu Chen; Sai-Juan Chen; Robert G Roeder; Shuhong Shen; Kai Xue; Xiao-Jian Sun
Journal:  Front Cell Dev Biol       Date:  2022-09-07
  2 in total

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