Literature DB >> 30738605

Translation to Practice: Accelerating the Cycle of Innovation to Impact.

Jeff R Anderson1, Thomas D Y Chung2, Leon Clark3, Jennifer A Weis3, Andrew J Danielsen4, Sundeep Khosla5, Gregory J Gores3, Andrew D Badley6.   

Abstract

The Office of Translation to Practice (OTP) is housed in the Center for Clinical and Translational Sciences at Mayo Clinic. Established in 2015, the office was tasked with developing and managing novel tools, mechanisms, and processes to facilitate and accelerate the translation of products, such as drugs, biological agents, and medical devices, into practice. Since its inception, the OTP is credited with creating valuable services through several strategic alliances and active scientific and project management involvement. The OTP continues to move forward to assist Mayo Clinic physicians and scientists to interact effectively with internal and external collaborators to advance translational projects that will benefit patients. Best practices, innovations, and nascent successes of the OTP are presented and discussed herein.
Copyright © 2018. Published by Elsevier Inc.

Entities:  

Mesh:

Year:  2019        PMID: 30738605      PMCID: PMC6853057          DOI: 10.1016/j.mayocp.2018.08.008

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  6 in total

1.  Translational research: 4 ways to fix the clinical trial.

Authors:  Heidi Ledford
Journal:  Nature       Date:  2011-09-28       Impact factor: 49.962

2.  The future of the postdoc.

Authors:  Kendall Powell
Journal:  Nature       Date:  2015-04-09       Impact factor: 49.962

3.  The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak.

Authors:  Amy M Sainski; Sekar Natesampillai; Nathan W Cummins; Gary D Bren; Julie Taylor; Dyana T Saenz; Eric M Poeschla; Andrew D Badley
Journal:  J Virol       Date:  2011-06-08       Impact factor: 5.103

4.  The $2.6 billion pill--methodologic and policy considerations.

Authors:  Jerry Avorn
Journal:  N Engl J Med       Date:  2015-05-14       Impact factor: 91.245

5.  Isolation of a TRAIL antagonist from the serum of HIV-infected patients.

Authors:  David J Schnepple; Brett Shepard; Gary D Bren; Nathan W Cummins; Sekar Natesampillai; Sergey Trushin; Alicia Algeciras-Schimnich; Xue W Meng; Amy M Sainski; Stacey A Rizza; Scott H Kaufmann; Andrew D Badley
Journal:  J Biol Chem       Date:  2011-08-22       Impact factor: 5.157

6.  Percutaneous Pericardial Resection: A Novel Potential Treatment for Heart Failure With Preserved Ejection Fraction.

Authors:  Barry A Borlaug; Rickey E Carter; Vojtech Melenovsky; Christopher V DeSimone; Prakriti Gaba; Ammar Killu; Niyada Naksuk; Lilach Lerman; Samuel J Asirvatham
Journal:  Circ Heart Fail       Date:  2017-04       Impact factor: 8.790

  6 in total

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