Literature DB >> 30728704

To Evaluate the Efficacy and Effectiveness of N-butyl-2-cyanoacrylate glue (TRU SEAL) in Closure of Oral and Maxillofacial Laceration and Surgical Incisions.

Praveen Kumar Singh1, Saikrishna Degala2, Sujeeth Shetty2, Vijay Singh Rai3, Asutosh Das3.   

Abstract

INTRODUCTION: Effective wound closure is critical for minimizing wound complications and preventing wound dehiscence. The various wound closure techniques include staples, traditional nylon and skin sutures, subcuticular sutures, and skin adhesives. Currently topical skin adhesives are frequently being used. It offers countless advantages: short application time, easy execution as well as possessing hemostatic character. N-butyl-2-cyanoacrylate is bacteriostatic and biodegradable and exhibits suitable tensile strength.
MATERIALS AND METHODS: Under nasoendotracheal intubation, the reduction in fracture and plating was done. In 80% of the patients, subcutaneous sutures were placed. Skin closure was done with N-butyl-2-cyanoacrylate glue.
RESULTS: In this study, REEDA scale was used to assess healing. Redness, edema, and ecchymosis were seen in all 10 patients, which subsided by the second week postoperatively. None of the patients had discharge from surgical site on the first postoperative day but was noted in two patients the first week postoperatively. There was evidence of wound gaping in one patient on the first postoperative day and two patients at end of the first week postoperatively. Stony Brook Scar Evaluation was used to evaluate postoperative cosmesis. No significant cosmetic impairment was found in all patients at the end of the study.
CONCLUSION: The study reflects qualitative assessment of cyanoacrylates which is simple to use and proper application which resulted in uniform and everted closure of wound. It is cost-efficient as compared to other wound closure materials.

Entities:  

Keywords:  Lacerations; N-butyl-2-cyanoacrylate glue; Surgical incisions; Tissue adhesive

Year:  2018        PMID: 30728704      PMCID: PMC6328818          DOI: 10.1007/s12663-018-1111-6

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  22 in total

1.  Efficacy of tissue glue for laceration repair in an animal model.

Authors:  M Yaron; M H Erin; W Huffer; C Cairns
Journal:  Acad Emerg Med       Date:  1995-04       Impact factor: 3.451

2.  A randomized, clinical trial comparing butylcyanoacrylate with octylcyanoacrylate in the management of selected pediatric facial lacerations.

Authors:  M H Osmond; J V Quinn; T Sutcliffe; M Jarmuske; T P Klassen
Journal:  Acad Emerg Med       Date:  1999-03       Impact factor: 3.451

3.  The effect of a new tissue-adhesive wound dressing on the healing of traumatic abrasions.

Authors:  J Quinn; L Lowe; M Mertz
Journal:  Dermatology       Date:  2000       Impact factor: 5.366

Review 4.  Surgical applications of cyanoacrylate adhesives: a review of toxicity.

Authors:  Peter A Leggat; Derek R Smith; Ureporn Kedjarune
Journal:  ANZ J Surg       Date:  2007-04       Impact factor: 1.872

5.  Histotoxicity of cyanoacrylate tissue adhesives. A comparative study.

Authors:  D M Toriumi; W F Raslan; M Friedman; M E Tardy
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1990-05

6.  A liquid adhesive bandage for the treatment of minor cuts and abrasions.

Authors:  William H Eaglstein; Tory P Sullivan; Philip A Giordano; Barry M Miskin
Journal:  Dermatol Surg       Date:  2002-03       Impact factor: 3.398

7.  An in-vivo study of the wound-bursting strengths of octyl-cyanoacrylate, butyl-cyanoacrylate, and surgical tape in rats.

Authors:  Breena R Taira; Adam J Singer; Jean Rooney; Nicole T Steinhauff; Thomas Zimmerman
Journal:  J Emerg Med       Date:  2009-01-31       Impact factor: 1.484

8.  Hemostatic effect of n-butyl-2-cyanoacrylate (histoacryl) glue in warfarin-treated patients undergoing oral surgery.

Authors:  Fouad A Al-Belasy; Maged Z Amer
Journal:  J Oral Maxillofac Surg       Date:  2003-12       Impact factor: 1.895

Review 9.  The cyanoacrylate topical skin adhesives.

Authors:  Adam J Singer; James V Quinn; Judd E Hollander
Journal:  Am J Emerg Med       Date:  2008-05       Impact factor: 2.469

10.  Incidence of hypertrophic and keloid scars after N-butyl 2-cyanoacrylate tissue adhesive had been used to close parotidectomy wounds: a prospective study of 100 consecutive patients.

Authors:  Gillian A Greenhill; Barry O'Regan
Journal:  Br J Oral Maxillofac Surg       Date:  2009-02-26       Impact factor: 1.651

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  1 in total

1.  Histological and microbiological evaluation of surgical wound closure in mouse skin with cyanoacrylate (Histoacryl®) in comparison to poliglecaprone (Monocryl®) traditional suture.

Authors:  A Villagomez; T Borja; P Pontón; G Segnini; P Barba; A Chiliquinga; I Yamberla; C Pupiales; D Suquillo; R F Díaz; F Cabrera; A Caicedo
Journal:  Vet Anim Sci       Date:  2021-05-24
  1 in total

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