Literature DB >> 3072067

Asn-linked oligosaccharide processing and malignant potential.

J W Dennis1.   

Abstract

There is now considerable evidence that malignant transformation is accompanied by many changes in the oligosaccharide structures of glycoproteins and glycolipids. More recently, studies using tumour cell glycosylation mutants and inhibitors of Asn-linked oligosaccharide processing have suggested that the transformation-associated increase in GlcNAc beta 1-6Man alpha 1-6 Man beta- branching of complex-type oligosaccharides may enhance tumour cell metastasis. The synthesis of beta 1-6 branched oligosaccharides and related structures as well as their possible function in cell-cell interactions and tumour cell metastasis are discussed.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3072067

Source DB:  PubMed          Journal:  Cancer Surv        ISSN： 0261-2429


  9 in total

1.  Changes in N-acetylglucosaminyltransferase III, IV and V in renal cell carcinoma.

Authors:  T Y Zhu; H L Chen; J X Gu; Y F Zhang; Y K Zhang; R A Zhang
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

2.  Structures of the alpha(1-3)-galactose-containing asparagine-linked glycans of a Lewis lung carcinoma cell subline resistant to Aleuria aurantia agglutinin: elucidation by 1H-NMR spectroscopy.

Authors:  H Debray; D Dus; J M Wieruszeski; G Strecker; J Montreuil
Journal:  Glycoconj J       Date:  1991-02       Impact factor: 2.916

Review 3.  Regulation of N-acetylglucosaminyltransferase V and Asn-linked oligosaccharide beta(1,6) branching by a growth factor signaling pathway and effects on cell adhesion and metastatic potential.

Authors:  M Pierce; P Buckhaults; L Chen; N Fregien
Journal:  Glycoconj J       Date:  1997-08       Impact factor: 2.916

4.  Alteration of N-acetylglucosaminyltransferases in pancreatic carcinoma.

Authors:  B C Nan; D M Shao; H L Chen; Y Huang; J X Gu; Y B Zhang; Z G Wu
Journal:  Glycoconj J       Date:  1998-10       Impact factor: 2.916

5.  Lectin-resistant variants of mouse Lewis lung carcinoma cells. I. Selection and in vivo properties.

Authors:  D Dus; H Debray; L Strzadala; J Rak; H Kusnierczyk; J Montreuil; C Radzikowski
Journal:  Clin Exp Metastasis       Date:  1990 May-Jun       Impact factor: 5.150

6.  Lectin-resistant variants of mouse Lewis lung carcinoma cells. II. Altered glycosylation of membrane glycoproteins.

Authors:  H Debray; D Dus; P Hueso; C Radzikowski; J Montreuil
Journal:  Clin Exp Metastasis       Date:  1990 May-Jun       Impact factor: 5.150

7.  Analysis of cell surface carbohydrate expression patterns in normal and tumorigenic human breast cell lines using lectin arrays.

Authors:  Siyuan Chen; Ting Zheng; Michael R Shortreed; Caroline Alexander; Lloyd M Smith
Journal:  Anal Chem       Date:  2007-06-20       Impact factor: 6.986

8.  Effect of retinoic acid on the structure of N-glycans on the surface of human hepatocarcinoma cells and its enzymatic mechanism.

Authors:  H L Chen; S C Dong; T Z Ju; X P Yang
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

9.  Colonial morphology of tumour cells and susceptibility to cytolysis by tumour necrosis factor. The role of cellular fibronectin deposition in the extracellular matrix.

Authors:  M L Neale; N Matthews
Journal:  Br J Cancer       Date:  1990-06       Impact factor: 7.640
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.