Literature DB >> 30715607

Diagnostic delay in patients with inflammatory bowel disease in Austria.

Gottfried Novacek1, Hans Peter Gröchenig2, Thomas Haas3, Heimo Wenzl4, Pius Steiner5, Robert Koch6, Thomas Feichtenschlager7, Gerald Eckhardt8, Andreas Mayer9, Andreas Kirchgatterer10, Othmar Ludwiczek11, Reingard Platzer12, Pavol Papay13, Johanna Gartner14, Harry Fuchssteiner15, Wolfgang Miehsler16, Paul-Gerhard Peters17, Gerhard Reicht18, Harald Vogelsang19, Clemens Dejaco19, Thomas Waldhör20.   

Abstract

BACKGROUND: Delayed diagnosis seems to be common in inflammatory bowel diseases (IBD). The study was carried out to investigate the diagnostic delay and associated risk factors in Austrian IBD patients.
METHODS: In a multicenter cross-sectional study adult patients with IBD attending 18 Austrian outpatient clinics completed a multi-item questionnaire that recorded medical and socioeconomic characteristics. The study outcome was diagnostic delay defined as the period from symptom onset to diagnosis of IBD.
RESULTS: A total of 1286 patients (Crohn's disease 830, ulcerative colitis 435, inflammatory bowel disease unclassified 21; females 651) with a median age of 40 years (interquartile range 31-52 years) and a median disease duration of 10 years (4-18 years) were analyzed. The median diagnostic delay was 6 months (2-23 months) in Crohn's disease and 3 months (1-10 months) in ulcerative colitis (p < 0.001). In the multivariable regression analysis Crohn's disease, greater age at diagnosis and a high educational level (compared to middle degree level) were independently associated with longer diagnostic delay.
CONCLUSION: The diagnostic delay was longer in Crohn's disease than in ulcerative colitis patients and was associated with greater age at diagnosis and a higher educational level.

Entities:  

Keywords:  Age at diagnosis; Crohn’s disease; Educational level; Surgery; Ulcerative colitis

Mesh:

Year:  2019        PMID: 30715607     DOI: 10.1007/s00508-019-1451-3

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  36 in total

1.  The Manitoba Inflammatory Bowel Disease Cohort Study: prolonged symptoms before diagnosis--how much is irritable bowel syndrome?

Authors:  Twila Burgmann; Ian Clara; Lesley Graff; John Walker; Lisa Lix; Patricia Rawsthorne; Cory McPhail; Linda Rogala; Norine Miller; Charles Noah Bernstein
Journal:  Clin Gastroenterol Hepatol       Date:  2006-04-17       Impact factor: 11.382

Review 2.  Ulcerative colitis.

Authors:  Silvio Danese; Claudio Fiocchi
Journal:  N Engl J Med       Date:  2011-11-03       Impact factor: 91.245

Review 3.  Long-term complications, extraintestinal manifestations, and mortality in adult Crohn's disease in population-based cohorts.

Authors:  Laurent Peyrin-Biroulet; Edward V Loftus; Jean-Frederic Colombel; William J Sandborn
Journal:  Inflamm Bowel Dis       Date:  2010-08-19       Impact factor: 5.325

Review 4.  Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review.

Authors:  Natalie A Molodecky; Ing Shian Soon; Doreen M Rabi; William A Ghali; Mollie Ferris; Greg Chernoff; Eric I Benchimol; Remo Panaccione; Subrata Ghosh; Herman W Barkema; Gilaad G Kaplan
Journal:  Gastroenterology       Date:  2011-10-14       Impact factor: 22.682

5.  Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial.

Authors:  Geert D'Haens; Filip Baert; Gert van Assche; Philip Caenepeel; Philippe Vergauwe; Hans Tuynman; Martine De Vos; Sander van Deventer; Larry Stitt; Allan Donner; Severine Vermeire; Frank J Van De Mierop; Jean-Charles R Coche; Janneke van der Woude; Thomas Ochsenkühn; Ad A van Bodegraven; Philippe P Van Hootegem; Guy L Lambrecht; Fazia Mana; Paul Rutgeerts; Brian G Feagan; Daniel Hommes
Journal:  Lancet       Date:  2008-02-23       Impact factor: 79.321

6.  Identification of a prodromal period in Crohn's disease but not ulcerative colitis.

Authors:  M Pimentel; M Chang; E J Chow; S Tabibzadeh; V Kirit-Kiriak; S R Targan; H C Lin
Journal:  Am J Gastroenterol       Date:  2000-12       Impact factor: 10.864

7.  Inflammatory Bowel Disease in South Limburg (the Netherlands) 1991-2002: Incidence, diagnostic delay, and seasonal variations in onset of symptoms.

Authors:  Mariëlle J L Romberg-Camps; Martine A M Hesselink-van de Kruijs; Leo J Schouten; Pieter C Dagnelie; Charles B Limonard; Arnold D M Kester; Laurens P Bos; Jelle Goedhard; Wim H A Hameeteman; Frank L Wolters; Maurice G V M Russel; Reinhold W Stockbrügger
Journal:  J Crohns Colitis       Date:  2009-02-12       Impact factor: 9.071

8.  Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data.

Authors:  Stefan Schreiber; Jean-Frédéric Colombel; Ralph Bloomfield; Susanna Nikolaus; Jürgen Schölmerich; Julian Panés; William J Sandborn
Journal:  Am J Gastroenterol       Date:  2010-03-16       Impact factor: 10.864

9.  Systematic evaluation of risk factors for diagnostic delay in inflammatory bowel disease.

Authors:  Stephan R Vavricka; Sabrina M Spigaglia; Gerhard Rogler; Valérie Pittet; Pierre Michetti; Christian Felley; Christian Mottet; Christian P Braegger; Daniela Rogler; Alex Straumann; Peter Bauerfeind; Michael Fried; Alain M Schoepfer
Journal:  Inflamm Bowel Dis       Date:  2011-04-20       Impact factor: 5.325

10.  Against quantiles: categorization of continuous variables in epidemiologic research, and its discontents.

Authors:  Caroline Bennette; Andrew Vickers
Journal:  BMC Med Res Methodol       Date:  2012-02-29       Impact factor: 4.615

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  6 in total

1.  Diagnostic Delay of Inflammatory Bowel Disease Is Significantly Higher in Public versus Private Health Care System in Mexican Patients.

Authors:  Jesús K Yamamoto-Furusho; Norma N Parra-Holguín
Journal:  Inflamm Intest Dis       Date:  2021-12-06

2.  Impact of Diagnostic Delay on Disease Course in Pediatric- versus Adult-Onset Patients with Ulcerative Colitis: Data from the Swiss IBD Cohort.

Authors:  Alain M Schoepfer; Vu Dang Chau Tran; Jean-Benoit Rossel; Christiane Sokollik; Johannes Spalinger; Ekaterina Safroneeva; Thea von Graffenried; Sébastien Godat; Dieter Hahnloser; Stephan R Vavricka; Christian Braegger; Andreas Nydegger
Journal:  Inflamm Intest Dis       Date:  2021-11-18

3.  The ulcerative colitis narrative Greece survey: patients' and physicians' perspective on quality of life and disease management.

Authors:  Nikos Viazis; Anastasia Stefanidou; Gerasimos J Mantzaris
Journal:  Ann Gastroenterol       Date:  2022-03-25

4.  Use of complementary and alternative medicine and low quality of life associate with the need for psychological and psychotherapeutic interventions in inflammatory bowel disease.

Authors:  Maximilian Kutschera; Thomas Waldhör; Gottfried Novacek; Wolfgang Miehsler; Hans Peter Gröchenig; Thomas Haas; Heimo Wenzl; Pius Steiner; Robert Koch; Thomas Feichtenschlager; Gerald Eckhardt; Andreas Mayer; Andreas Kirchgatterer; Othmar Ludwiczek; Reingard Platzer; Pavol Papay; Johanna Gartner; Harry Fuchssteiner; Paul-Gerhard Peters; Gerhard Reicht; Gabriele Moser; Clemens Dejaco; Harald Vogelsang; Christian Primas
Journal:  United European Gastroenterol J       Date:  2021-02-18       Impact factor: 4.623

5.  Diagnostic Delay in Paediatric Inflammatory Bowel Disease-A Systematic Investigation.

Authors:  Bahareh Sophia Khalilipour; Andrew S Day; Kristin Kenrick; Michael Schultz; Kristina Aluzaite
Journal:  J Clin Med       Date:  2022-07-18       Impact factor: 4.964

Review 6.  Diagnosis and natural history of preclinical and early inflammatory bowel disease.

Authors:  Iago Rodríguez-Lago; Yamile Zabana; Manuel Barreiro-de Acosta
Journal:  Ann Gastroenterol       Date:  2020-06-22
  6 in total

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