| Literature DB >> 30712316 |
Zeynep Eroglu1, Sheri L Holmen2, Qing Chen3, Nikhil I Khushalani1, Ravi Amaravadi4, Reena Thomas5, Kamran A Ahmed1, Hussein Tawbi6, Sunandana Chandra7, Joseph Markowitz1, Inna Smalley1, James K C Liu1, Yian Ann Chen1, Yana G Najjar8, Florian A Karreth1, Daniel Abate-Daga1, Isabella C Glitza6, Jeffrey A Sosman7, Vernon K Sondak1, Marcus Bosenberg9, Meenhard Herlyn3, Michael B Atkins10, Harriet Kluger9, Kim Margolin11, Peter A Forsyth1, Michael A Davies6, Keiran S M Smalley1.
Abstract
In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.Entities:
Keywords: brain metastases; immunotherapy; melanoma; metastasis; targeted therapy
Mesh：
Year: 2019 PMID： 30712316 DOI： 10.1111/pcmr.12771
Source DB: PubMed Journal: Pigment Cell Melanoma Res ISSN： 1755-1471 Impact factor: 4.693