Mauro Neri1, Anna Lorenzin2, Massimo de Cal2, Alessandra Brendolan2, Nicola Marchionna2, Sara Samoni2, Monica Zanella2, Silvia De Rosa3, Francesca Martino2, Zaccaria Ricci4, Javier Maynar5, Georg Auzinger6, Gianluca Villa7, Didier Payen8, Michael Joannidis9, Claudio Ronco2. 1. Department of Nephrology, Dialysis and Transplantation and International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy, neri.mauro@gmail.com. 2. Department of Nephrology, Dialysis and Transplantation and International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy. 3. Department of Anesthesiology and Intensive Care, San Bortolo Hospital, Vicenza, Italy. 4. Department of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS Rome, Rome, Italy. 5. Intensive Care Unit, University Hospital Araba, Vitoria-Gasteiz, Spain. 6. King's College Hospital, Denmark Hill, London, United Kingdom. 7. Department of Health Sciences, Section of Anaesthesiology, Intensive Care and Pain, University of Florence, Florence, Italy. 8. University Paris Diderot, Sorbonne Paris Cité, Paris, France. 9. Division of Emergency Medicine and Intensive Care, Department Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
Abstract
BACKGROUND: ACUsmart (Medica S.P.A., Italy) is a new-generation, continuous renal replacement therapy (CRRT) machine for critically ill patients with acute kidney injury. We designed a multicenter international pilot study to provide a description of outlines of the ACUsmart system, evaluation aspects of functionality, usability, and feasibility, discriminating reasons of possible treatment's withdrawals or discontinuations and highlighting strong and weak points of the machine. METHODS: Data of 23 CRRT (and 11 plasma exchange) treatments were collected from 4 intensive care units. Parameters such as treatment duration, downtime, delivered dose, and number and type of alarms were recorded. The general perception of the machine was quantified through the administration of a survey to each component of the evaluating staff. RESULTS: A total treatment time of 447 h was carried with ACUsmart. Eleven continuous veno-venous hemofiltration, 4 continuous veno-venous hemodialysis , and 8 continuous veno-venous hemodiafiltration were performed. The average percentage of net treatment duration with respect to total treatment duration was 92.37%. The mean prescribed dose and delivered dose were 26.33 and 24.10 mL/kg/h, respectively. In general, the machine was rated by users involved as practical and easy to use, although few components need to be slightly improved. CONCLUSION: ACUsmart is a new multifunctional machine that meets most of the features required in a fourth-generation CRRT equipment.
BACKGROUND: ACUsmart (Medica S.P.A., Italy) is a new-generation, continuous renal replacement therapy (CRRT) machine for critically illpatients with acute kidney injury. We designed a multicenter international pilot study to provide a description of outlines of the ACUsmart system, evaluation aspects of functionality, usability, and feasibility, discriminating reasons of possible treatment's withdrawals or discontinuations and highlighting strong and weak points of the machine. METHODS: Data of 23 CRRT (and 11 plasma exchange) treatments were collected from 4 intensive care units. Parameters such as treatment duration, downtime, delivered dose, and number and type of alarms were recorded. The general perception of the machine was quantified through the administration of a survey to each component of the evaluating staff. RESULTS: A total treatment time of 447 h was carried with ACUsmart. Eleven continuous veno-venous hemofiltration, 4 continuous veno-venous hemodialysis , and 8 continuous veno-venous hemodiafiltration were performed. The average percentage of net treatment duration with respect to total treatment duration was 92.37%. The mean prescribed dose and delivered dose were 26.33 and 24.10 mL/kg/h, respectively. In general, the machine was rated by users involved as practical and easy to use, although few components need to be slightly improved. CONCLUSION: ACUsmart is a new multifunctional machine that meets most of the features required in a fourth-generation CRRT equipment.
Authors: Raghavan Murugan; Eric Hoste; Ravindra L Mehta; Sara Samoni; Xiaoqiang Ding; Mitchell H Rosner; John A Kellum; Claudio Ronco Journal: Blood Purif Date: 2016-08-26 Impact factor: 2.614
Authors: William R Clark; Mauro Neri; Francesco Garzotto; Zaccaria Ricci; Stuart L Goldstein; Xiaoqiang Ding; Jiarui Xu; Claudio Ronco Journal: Crit Care Date: 2017-04-11 Impact factor: 9.097
Authors: Gianluca Villa; Mauro Neri; Rinaldo Bellomo; Jorge Cerda; A Raffaele De Gaudio; Silvia De Rosa; Francesco Garzotto; Patrick M Honore; John Kellum; Anna Lorenzin; Didier Payen; Zaccaria Ricci; Sara Samoni; Jean-Louis Vincent; Julia Wendon; Marta Zaccaria; Claudio Ronco Journal: Crit Care Date: 2016-10-10 Impact factor: 9.097