Literature DB >> 30710133

Mapping biologically active chemical space to accelerate drug discovery.

G Sitta Sittampalam, Dobrila D Rudnicki, Danilo A Tagle, Anton Simeonov, Christopher P Austin.   

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Year:  2019        PMID: 30710133      PMCID: PMC7040855          DOI: 10.1038/d41573-018-00007-2

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  5 in total

Review 1.  Automating drug discovery.

Authors:  Gisbert Schneider
Journal:  Nat Rev Drug Discov       Date:  2017-12-15       Impact factor: 84.694

2.  The drug-maker's guide to the galaxy.

Authors:  Asher Mullard
Journal:  Nature       Date:  2017-09-26       Impact factor: 49.962

3.  AI designs organic syntheses.

Authors:  Derek Lowe
Journal:  Nature       Date:  2018-03-29       Impact factor: 49.962

Review 4.  Unexplored therapeutic opportunities in the human genome.

Authors:  Tudor I Oprea; Cristian G Bologa; Søren Brunak; Allen Campbell; Gregory N Gan; Anna Gaulton; Shawn M Gomez; Rajarshi Guha; Anne Hersey; Jayme Holmes; Ajit Jadhav; Lars Juhl Jensen; Gary L Johnson; Anneli Karlson; Andrew R Leach; Avi Ma'ayan; Anna Malovannaya; Subramani Mani; Stephen L Mathias; Michael T McManus; Terrence F Meehan; Christian von Mering; Daniel Muthas; Dac-Trung Nguyen; John P Overington; George Papadatos; Jun Qin; Christian Reich; Bryan L Roth; Stephan C Schürer; Anton Simeonov; Larry A Sklar; Noel Southall; Susumu Tomita; Ilinca Tudose; Oleg Ursu; Dušica Vidovic; Anna Waller; David Westergaard; Jeremy J Yang; Gergely Zahoránszky-Köhalmi
Journal:  Nat Rev Drug Discov       Date:  2018-03-23       Impact factor: 84.694

5.  The promise and peril of chemical probes.

Authors:  Cheryl H Arrowsmith; James E Audia; Christopher Austin; Jonathan Baell; Jonathan Bennett; Julian Blagg; Chas Bountra; Paul E Brennan; Peter J Brown; Mark E Bunnage; Carolyn Buser-Doepner; Robert M Campbell; Adrian J Carter; Philip Cohen; Robert A Copeland; Ben Cravatt; Jayme L Dahlin; Dashyant Dhanak; Aled M Edwards; Mathias Frederiksen; Stephen V Frye; Nathanael Gray; Charles E Grimshaw; David Hepworth; Trevor Howe; Kilian V M Huber; Jian Jin; Stefan Knapp; Joanne D Kotz; Ryan G Kruger; Derek Lowe; Mary M Mader; Brian Marsden; Anke Mueller-Fahrnow; Susanne Müller; Ronan C O'Hagan; John P Overington; Dafydd R Owen; Saul H Rosenberg; Bryan Roth; Brian Roth; Ruth Ross; Matthieu Schapira; Stuart L Schreiber; Brian Shoichet; Michael Sundström; Giulio Superti-Furga; Jack Taunton; Leticia Toledo-Sherman; Chris Walpole; Michael A Walters; Timothy M Willson; Paul Workman; Robert N Young; William J Zuercher
Journal:  Nat Chem Biol       Date:  2015-08       Impact factor: 15.040

  5 in total
  3 in total

Review 1.  Advances in preclinical approaches to Chagas disease drug discovery.

Authors:  Fernando Villalta; Girish Rachakonda
Journal:  Expert Opin Drug Discov       Date:  2019-08-14       Impact factor: 6.098

2.  Exploring Novel Biologically-Relevant Chemical Space Through Artificial Intelligence: The NCATS ASPIRE Program.

Authors:  Katharine K Duncan; Dobrila D Rudnicki; Christopher P Austin; Danilo A Tagle
Journal:  Front Robot AI       Date:  2020-01-10

Review 3.  Opportunities and challenges in translational science.

Authors:  Christopher P Austin
Journal:  Clin Transl Sci       Date:  2021-07-08       Impact factor: 4.689

  3 in total

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