Literature DB >> 30705528

Improvising PRP for use in osteoarthritis knee- upcoming trends and futuristic view.

Mandeep S Dhillon1, Sandeep Patel1, Tungish Bansal2.   

Abstract

Platelet rich plasma (PRP) has clearly emerged offering a possible solution that could modify the disease process and offer symptomatic relief in early osteoarthritis of knee. Great efforts are underway to improve PRP products for use in knee osteoarthritis (OA). Upcoming research is focused on the ideal PRP type, dose, frequency of injection and mode of injection. The combination of PRP with biocompatible carriers/scaffolds like gelatin hydrogel and chitosan appear to be promising based on early in vitro and animal studies. PRP in combination with hyaluronate has also emerged to have synergistic and additive effects. This article intends to review the recent trends and advancing ideas for improvising PRP for use in early knee OA treatment.

Entities:  

Keywords:  Osteoarthritis knee; PRP; Scaffolds

Year:  2018        PMID： 30705528      PMCID： PMC6349634          DOI： 10.1016/j.jcot.2018.10.005

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN： 0976-5662


  38 in total

1.  Intra-articular injection of an autologous preparation rich in growth factors for the treatment of knee OA: a retrospective cohort study.

Authors:  M Sánchez; E Anitua; J Azofra; J J Aguirre; I Andia
Journal:  Clin Exp Rheumatol       Date:  2008 Sep-Oct       Impact factor: 4.473

2.  Plasma rich in growth factors (PRGF-Endoret) stimulates tendon and synovial fibroblasts migration and improves the biological properties of hyaluronic acid.

Authors:  E Anitua; M Sanchez; M De la Fuente; M M Zalduendo; G Orive
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-10-11       Impact factor: 4.342

Review 3.  Viscosupplementation with intra-articular hyaluronic acid for treatment of osteoarthritis in the elderly.

Authors:  M Abate; D Pulcini; A Di Iorio; C Schiavone
Journal:  Curr Pharm Des       Date:  2010       Impact factor: 3.116

Review 4.  Sports medicine applications of platelet rich plasma.

Authors:  Allan Mishra; Kimberly Harmon; James Woodall; Amy Vieira
Journal:  Curr Pharm Biotechnol       Date:  2012-06       Impact factor: 2.837

5.  Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes: mechanisms of NF-κB inhibition via HGF.

Authors:  Paola Bendinelli; Emanuela Matteucci; Giada Dogliotti; Massimiliano M Corsi; Giuseppe Banfi; Paola Maroni; Maria Alfonsina Desiderio
Journal:  J Cell Physiol       Date:  2010-11       Impact factor: 6.384

6.  Enhanced vascularization by controlled release of platelet-rich plasma impregnated in biodegradable gelatin hydrogel.

Authors:  Jiro Kurita; Masaaki Miyamoto; Yosuke Ishii; Junya Aoyama; Gen Takagi; Zenya Naito; Yasuhiko Tabata; Masami Ochi; Kazuo Shimizu
Journal:  Ann Thorac Surg       Date:  2011-09       Impact factor: 4.330

7.  Releasing growth factors from activated human platelets after chitosan stimulation: a possible bio-material for platelet-rich plasma preparation.

Authors:  E-Chin Shen; Tz-Chong Chou; Ching-Hwa Gau; Hsiao-Pei Tu; Yen-Teen Chen; Earl Fu
Journal:  Clin Oral Implants Res       Date:  2006-10       Impact factor: 5.977

8.  Platelet-rich plasma intra-articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis.

Authors:  Giuseppe Filardo; Elizaveta Kon; Roberto Buda; Antonio Timoncini; Alessandro Di Martino; Annarita Cenacchi; Pier Maria Fornasari; Sandro Giannini; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-08-26       Impact factor: 4.342

9.  Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients.

Authors:  E Anitua; M Sánchez; A T Nurden; M M Zalduendo; M de la Fuente; J Azofra; I Andía
Journal:  Rheumatology (Oxford)       Date:  2007-10-17       Impact factor: 7.580

10.  Intraarticular administration of platelet-rich plasma with biodegradable gelatin hydrogel microspheres prevents osteoarthritis progression in the rabbit knee.

Authors:  M Saito; K A Takahashi; Y Arai; A Inoue; K Sakao; H Tonomura; K Honjo; S Nakagawa; H Inoue; Y Tabata; T Kubo
Journal:  Clin Exp Rheumatol       Date:  2009 Mar-Apr       Impact factor: 4.473
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  8 in total

1.  Intelligent Algorithm-Based Magnetic Resonance for Evaluating the Effect of Platelet-Rich Plasma in the Treatment of Intractable Pain of Knee Arthritis.

Authors:  Bing Huang; Yun Huang; Xin Ma; Yuequn Chen
Journal:  Contrast Media Mol Imaging       Date:  2022-05-26       Impact factor: 3.009

2.  Preparation and Characterization of Plasma-Derived Fibrin Hydrogels Modified by Alginate di-Aldehyde.

Authors:  Raúl Sanz-Horta; Ana Matesanz; José Luis Jorcano; Diego Velasco; Pablo Acedo; Alberto Gallardo; Helmut Reinecke; Carlos Elvira
Journal:  Int J Mol Sci       Date:  2022-04-13       Impact factor: 6.208

3.  Consecutive injections of leukocyte-rich platelet-rich plasma are effective in not only mild but also severe knee degeneration.

Authors:  Masahiko Kemmochi
Journal:  J Orthop       Date:  2022-01-19

4.  Effects of platelet-rich plasma injection for pain control and cartilage repair in knee osteoarthritis: A protocol for the systematic review and meta-analysis of randomized controlled trials in animal models.

Authors:  Li Bocun; Li Jing; Li Jia; Qian Tan; Jianyi Chen; Zhongsheng Huang; Cai Guowei
Journal:  Medicine (Baltimore)       Date:  2021-01-08       Impact factor: 1.817

5.  Efficacy of Platelet-Rich Plasma on Pain and Function in the Treatment of Knee Osteoarthritis: A Prospective Cohort Study.

Authors:  Adel H Hegaze; Amre S Hamdi; Abdulraof Alqrache; Mohamed Hegazy
Journal:  Cureus       Date:  2021-03-15

Review 6.  Overview of First-Line and Second-Line Pharmacotherapies for Osteoarthritis with Special Focus on Intra-Articular Treatment.

Authors:  Alicja Nowaczyk; Dawid Szwedowski; Ignacio Dallo; Jacek Nowaczyk
Journal:  Int J Mol Sci       Date:  2022-01-29       Impact factor: 5.923

7.  Clinical Response After Treatment of Knee Osteoarthritis With a Standardized, Closed-System, Low-Cost Platelet-Rich Plasma Product: 1-Year Outcomes.

Authors:  Judit Fernández-Fuertes; Tamara Arias-Fernández; Andrea Acebes-Huerta; Marlene Álvarez-Rico; Laura Gutiérrez
Journal:  Orthop J Sports Med       Date:  2022-03-31

8.  Effect of Fibrin Concentration on the In Vitro Production of Dermo-Epidermal Equivalents.

Authors:  Andrés Montero; Cristina Quílez; Leticia Valencia; Paula Girón; José Luis Jorcano; Diego Velasco
Journal:  Int J Mol Sci       Date:  2021-06-23       Impact factor: 5.923
  8 in total

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