Conditional Generative Adversarial Networks for Metal Artifact Reduction in CT Images of the Ear.

We propose an approach based on a conditional generative adversarial network (cGAN) for the reduction of metal artifacts (RMA) in computed tomography (CT) ear images of cochlear implants (CIs) recipients. Our training set contains paired pre-implantation and post-implantation CTs of 90 ears. At the training phase, the cGAN learns a mapping from the artifact-affected CTs to the artifact-free CTs. At the inference phase, given new metal-artifact-affected CTs, the cGAN produces CTs in which the artifacts are removed. As a pre-processing step, we also propose a band-wise normalization method, which splits a CT image into three channels according to the intensity value of each voxel and we show that this method improves the performance of the cGAN. We test our cGAN on post-implantation CTs of 74 ears and the quality of the artifact-corrected images is evaluated quantitatively by comparing the segmentations of intra-cochlear anatomical structures, which are obtained with a previously published method, in the real pre-implantation and the artifact-corrected CTs. We show that the proposed method leads to an average surface error of 0.18 mm which is about half of what could be achieved with a previously proposed technique.