Literature DB >> 30691716

Modulation of Bronchomotor Tone Pathways in Airway Smooth Muscle Function and Bronchomotor Tone in Asthma.

Cynthia J Koziol-White1, Reynold A Panettieri2.   

Abstract

Airway smooth muscle is the primary cell mediating bronchomotor tone. The milieu created in the asthmatic lung modulates airway smooth muscle contractility and relaxation. Experimental findings suggest intrinsic abnormalities in airway smooth muscle derived from patients with asthma in comparison with airway smooth muscle from those without asthma. These changes to excitation-contraction pathways may underlie airway hyperresponsiveness and increased airway resistance associated with asthma.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Airway obstruction; Airway remodeling; Asthma; Bronchoconstriction; Bronchodilation

Mesh：

Substances：

Year:  2018        PMID： 30691716      PMCID： PMC6410362          DOI： 10.1016/j.ccm.2018.10.003

Source DB:  PubMed          Journal:  Clin Chest Med        ISSN： 0272-5231            Impact factor:   2.878


  43 in total

1.  Tumour necrosis factor-alpha activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle.

Authors:  J R Parris; H J Cobban; A F Littlejohn; D J MacEwan; G F Nixon
Journal:  J Physiol       Date:  1999-07-15       Impact factor: 5.182

2.  Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases.

Authors:  Joseph A Jude; Krishnaswamy G Tirumurugaan; Bit Na Kang; Reynold A Panettieri; Timothy F Walseth; Mathur S Kannan
Journal:  Am J Respir Cell Mol Biol       Date:  2012-05-03       Impact factor: 6.914

3.  Sphingosine 1-phosphate causes airway hyper-reactivity by rho-mediated myosin phosphatase inactivation.

Authors:  Hiroaki Kume; Naoya Takeda; Tetsuya Oguma; Satoru Ito; Masashi Kondo; Yasushi Ito; Kaoru Shimokata
Journal:  J Pharmacol Exp Ther       Date:  2006-11-14       Impact factor: 4.030

Review 4.  Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

Authors:  S S An; T R Bai; J H T Bates; J L Black; R H Brown; V Brusasco; P Chitano; L Deng; M Dowell; D H Eidelman; B Fabry; N J Fairbank; L E Ford; J J Fredberg; W T Gerthoffer; S H Gilbert; R Gosens; S J Gunst; A J Halayko; R H Ingram; C G Irvin; A L James; L J Janssen; G G King; D A Knight; A M Lauzon; O J Lakser; M S Ludwig; K R Lutchen; G N Maksym; J G Martin; T Mauad; B E McParland; S M Mijailovich; H W Mitchell; R W Mitchell; W Mitzner; T M Murphy; P D Paré; R Pellegrino; M J Sanderson; R R Schellenberg; C Y Seow; P S P Silveira; P G Smith; J Solway; N L Stephens; P J Sterk; A G Stewart; D D Tang; R S Tepper; T Tran; L Wang
Journal:  Eur Respir J       Date:  2007-05       Impact factor: 16.671

5.  Store-operated Ca2+ entry is involved in transforming growth factor-β1 facilitated proliferation of rat airway smooth muscle cells.

Authors:  Ya-Dong Gao; Jun-Wen Zheng; Ping Li; Ming Cheng; Jiong Yang
Journal:  J Asthma       Date:  2013-05-07       Impact factor: 2.515

Review 6.  Eicosanoids in asthma, allergic inflammation, and host defense.

Authors:  Joshua A Boyce
Journal:  Curr Mol Med       Date:  2008-08       Impact factor: 2.222

Review 7.  Calcium signaling in airway smooth muscle.

Authors:  Joseph A Jude; Mark E Wylam; Timothy F Walseth; Mathur S Kannan
Journal:  Proc Am Thorac Soc       Date:  2008-01-01

8.  Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein.

Authors:  Yoshihiko Chiba; Shuji Nakazawa; Michiko Todoroki; Koji Shinozaki; Hiroyasu Sakai; Miwa Misawa
Journal:  Am J Respir Cell Mol Biol       Date:  2008-08-07       Impact factor: 6.914

9.  TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation.

Authors:  Philip R Cooper; Roberta Lamb; Nicole D Day; Patrick J Branigan; Radhika Kajekar; Lani San Mateo; Pamela J Hornby; Reynold A Panettieri
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2009-06-19       Impact factor: 5.464

10.  Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1.

Authors:  Yasin Shaifta; Charles E MacKay; Nneka Irechukwu; Katie A O'Brien; David B Wright; Jeremy P T Ward; Greg A Knock
Journal:  J Physiol       Date:  2017-11-23       Impact factor: 5.182
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  5 in total

1.  Bronchodilator Dose Responsiveness in Children and Adolescents: Clinical Features and Association with Future Asthma Exacerbations.

Authors:  Jocelyn R Grunwell; Khristopher M Nguyen; Alice C Bruce; Anne M Fitzpatrick
Journal:  J Allergy Clin Immunol Pract       Date:  2019-10-12

2.  ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility.

Authors:  Alexa K Pham; Marina Miller; Peter Rosenthal; Sudipta Das; Ning Weng; Sunghoon Jang; Richard C Kurten; Jana Badrani; Taylor A Doherty; Brian Oliver; David H Broide
Journal:  JCI Insight       Date:  2021-04-08

3.  Airway smooth muscle and airway hyperresponsiveness in asthma: mechanisms of airway smooth muscle dysfunction.

Authors:  Eric B Gebski; Omkar Anaspure; Reynold A Panettieri; Cynthia J Koziol-White
Journal:  Minerva Med       Date:  2021-01-26       Impact factor: 5.580

Review 4.  Targeting cell signaling in allergic asthma.

Authors:  Seyyed Shamsadin Athari
Journal:  Signal Transduct Target Ther       Date:  2019-10-18

5.  Dandelion extract relaxes mouse airway smooth muscle by blocking VDLCC and NSCC channels.

Authors:  Ping Zhao; Jia Liu; Qian Ming; Di Tian; Jingwen He; Ziwei Yang; Jinhua Shen; Qing-Hua Liu; Xinzhou Yang
Journal:  Cell Biosci       Date:  2020-10-28       Impact factor: 7.133
  5 in total

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