| Literature DB >> 30684803 |
Mohit Kumar1, Shweta Jaiswal2, Kushneet Kaur Sodhi1, Pallee Shree1, Dileep Kumar Singh1, Pawan Kumar Agrawal3, Pratyoosh Shukla4.
Abstract
Antibiotic is one of the most significant discoveries and have brought a revolution in the field of medicine for human therapy. In addition to the medical uses, antibiotics have broad applications in agriculture and animal husbandry. In developing nations, antibiotics use have helped to increase the life expectancy by lowering the deaths due to bacterial infections, but the risks associated with antibiotics pollution is largely affecting people. Since antibiotics are released partially degraded and undegraded into environment creating antibiotic pollution, and its bioremediation is a challenging task. In the present review, we have discussed the primary antibiotic sources like hospitals, dairy, and agriculture causing antibiotic pollution and their innovative detection methods. The strong commitment towards the resistance prevention and participation, nations through strict policies and their implementations now come to fight against the antibiotic resistance under WHO. The review also deciphers the bacterial evolution based strategies to overcome the effects of antibiotics, so the antibiotic degradation and elimination from the environment and its health benefits. The present review focuses on the environmental sources of antibiotics, it's possible degradation mechanisms, health effects, and bacterial antibiotics resistance mechanisms.Entities:
Keywords: Antibiotics; Biofilm; Bioremediation; Degradation; Microbial consortium
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Year: 2019 PMID: 30684803 DOI: 10.1016/j.envint.2018.12.065
Source DB: PubMed Journal: Environ Int ISSN: 0160-4120 Impact factor: 9.621